非球面散光矫正型人工晶状体的临床应用研究

目的评价非球面散光矫正型人工晶状体临床应用效果。方法79例（92只眼）年龄相关性白内障随机分为两组：A组，39例（49只眼）行超声乳化吸出非球面散光矫正型人工晶状体植入术；B组，40例（43只眼）行超声乳化吸出普通非球面人工晶状体植入。观察两组的术后视力、对比敏感度及波前像差，进行统计学分析。结果术后3个月，两组术眼的裸眼远视力、裸眼近视力差异有统计学意义（t=9．218、8．667，P=0．001、0．002）；两组间矫正远视力、矫正近视力差异无统计学意义（t=1．657、1．108，P=0．174、0．275）；两组术后残余散光度差异有统计学意义（t=4．029，P=0．005）；两组总体高阶像差差异有统计学意义（t=3．136，P=0．008），3阶像差、4阶像差和5阶像差的均方根值之间差异无统计学意义（t=1．387、1．670、1．236，P：0．173、0．134、0．247）；两组术眼的对比敏感度在任何空间频率上阈值差异有统计学意义（t=3．367、2．984、4．235、3．816、2．564、5．987、2．437、4．207，P=0．009、0．025、0．002、0．0025、0．007、0．0005、0．045、0．001）。结论白内障行超声乳化吸出联合非球面散光矫正型人工晶状体植入可使术眼获得更好的视觉质量，是矫正白内障患者术前角膜散光的一种有效方法。

Study on the clinical application of AcrySof IQ Toric intraocular lens

Objective To evaluate the clinical efficacy of aspherical astigmatism-corrected intraocular lens （IOL）. Methods Ninety-two eyes of 79 patients with age-related cataract underwent phacoemulsification and was randomly divided into 2 groups. In group A, the AcrySof IQ Toric IOL was implanted in 49 eyes of 39 patients. In group B, the aspherical IOL was implanted in 43 eyes of 40 patients. Three months ＇after surgery, the visual acuity, higher-order aberrations and contrast sensitivity were evaluated and statistically analyzed. Results At 3 months after surgery, the differences of uncorrected near and distance visual acuities were statistically significant between two groups （t = 9. 218,8. 667, P = 0. 001, 0. 002）; There were no significant differences in the corrected distant and corrected near visual acuity between two groups （ t = 1. 657,1. 108 ,P = 0. 174,0. 275 ） ; There was significant difference in postoperative residual corneal astigmatism between two groups （t =4. 029 ,P = 0. 005 ） ; There was significant difference in the general higher-order aberrations root mean square value between two groups （t = 3.136, P = 0. 008 ）, and there were no statistically significant differences in 3-order aberrations, 4-order aberrations, and 5-order aberrations root mean square value between two groups （t-=1. 387,1. 670, 1. 236, P = 0. 173,0. 134, 0. 247） ; There were significant differences at all spatial frequencies of contrast sensitivity function between two groups （ t = 3. 367,2. 984,4. 235,3. 816,2. 564,5. 987,2. 437,4. 207, P = 0. 009,0. 025,0. 002, 0. 0025,0.007,0. 0005,0. 045,0. 001 ）. Conclusion Phaeoemulsification combined with AcrySof IQ Toric IOL implantation is an effective method for the correction of preexisting corneal astigmatism and brings better optical quality for cataract patients.