| 氟哌利多与氟哌啶醇治疗急性躁狂症的比较 |
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| 引用本文： | 曾昭祥,黄建军,朱爱兰,陈景清,申连城,于兴旺,李志成.氟哌利多与氟哌啶醇治疗急性躁狂症的比较[J].中国新药与临床杂志,1994(6). |
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| 作者姓名： | 曾昭祥 黄建军 朱爱兰 陈景清 申连城 于兴旺 李志成 |
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| 作者单位： | 山东省济宁市精神病防治院 |
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| 摘 要： | ３４例急性躁狂症随机分配至氟哌利多组（男性１１例，女性７例；年龄２８±ｓ１０ａ）和氟哌啶醇组（男性１０例，女性６例；年龄２９±１２ａ）治疗。２药的治疗剂量均为１０－２０ｍｇ，ｉｍ，ｂｉｄ，疗程２ｗｋ。用ＢＲＭＳ、ＣＧＩ－ＳＩ、ＧＡＳ及ＴＥＳＳ量表评定。结果显示：２药疗效相仿：２组ＢＲＭＳ和ＣＧＩ－ＳＩ总分的减分及ＧＡＳ总分的增分差异不显著（Ｐ＞０．０５）；２药主要不良反应为锥体外系反应。
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| 关 键 词： | 氟哌利多 氟哌啶醇：躁狂性精神病 |
Droperidol vs haloperidol in treatment of acute mania |
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| ZENG Zhao-Xiang,HUANG Jian-Jun, ZHU Ai-Lan, CHEN Jing-Qing, SHEN Lian-Cheng,YU Xing-Wang,LI Zhi-Cheng.Droperidol vs haloperidol in treatment of acute mania[J].Chinese Journal of New Drugs and Clinical Remedies,1994(6). |
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| Authors: | ZENG Zhao-Xiang HUANG Jian-Jun ZHU Ai-Lan CHEN Jing-Qing SHEN Lian-Cheng YU Xing-Wang LI Zhi-Cheng |
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| Abstract: | Thirty-four patients with acute mania were divided into group of droperidol (M 11,F 7;age 28±s 10 a)and that of haloperidol(M 10, F6;age 29±12 a) at random. The dosage of both drugs were 10-20 mg,im,bid for 2 wk.Their symptoms were assessed with BRMS, CGI-SI,GAS and TESS before and after therapy.Results showed that efficacious of two drugs were almost the same,the decrease of BRMS, CGI-SI total scores and the increase of GAS total scores between two drugs had no significant difference(P>0.05).The common adverse reactions of both drugs were myotonia, tremor,and akathisia. |
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| Keywords: | droperidol haloperidol manic disorder |
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