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特比奈芬治疗88例儿童甲真菌病临床观察
引用本文:温炬,林中方.特比奈芬治疗88例儿童甲真菌病临床观察[J].第一军医大学学报,2005,25(5):582-583.
作者姓名:温炬  林中方
作者单位:广东省第二人民医院皮肤科,广东广州510317
摘    要:目的 观察特比奈芬治疗儿童甲真菌病的疗效及安全性。方法 应用特比奈芬治疗儿童指甲真菌病50例及趾甲真菌病38例,并作疗效、真菌清除率及安全性观察。结果 特比奈芬治疗儿童指甲真菌病的痊愈率及总有效率分别为92.1%和97-37%:趾甲真菌病则分别为86.36%和93.94%。真菌清除率均达到96.59%。在本临床研究中未发现特比奈芬有严重的毒副反应。结论 特比奈芬治疗儿童甲真菌病疗效显著、安全性高,是有效根治儿童甲真菌病的方法之一。

关 键 词:特比奈芬  甲真菌病  临床观察

Effect of terbinafine in treating onychomycosis in children: clinical observation of 88 cases]
Ju Wen,Zhong-fang Lin.Effect of terbinafine in treating onychomycosis in children: clinical observation of 88 cases][J].Journal of First Military Medical University,2005,25(5):582-583.
Authors:Ju Wen  Zhong-fang Lin
Institution:Department of Dermatology, Second People's Hospital of Guangdong Province, Guangzhou 510317, China.
Abstract:OBJECTIVE: To observe the therapeutic effect and safety of terbinafine in treating onychomycosis in children. METHODS: Terbinafine was used to treat 50 children with fingernail onychomycosis and 38 with toenail onychomycosis, and the efficacy, fungal clearance and safety of the drug were evaluated. RESULTS: The clinical cure rate and total effective rate were 92.1% and 97.37%, respectively, for fingernail onychomycosis, and 86.36% and 93.94% for toenail onychomycosis, with fungal clearance rate of 96.59%. No serious side-effects was observed in the children receiving terbinafine therapy. CONCLUSION: Terbinafine is effective and safe for the treatment of onychomycosis in children.
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