| 脐血和成人外周血细胞免疫活性的区别 |
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| 引用本文： | 李建蓉,王晶. 脐血和成人外周血细胞免疫活性的区别[J]. 大理医学院学报, 1996, 0(4) |
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| 作者姓名： | 李建蓉 王晶 |
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| 摘 要： | 脐血中富含多种造血细胞，可移植治疗实体瘤等疾病。本文采用间接免疫荧光法与淋巴细胞转化试验，比较脐血与成人外周血Ｔ细胞亚群和淋巴细胞转化率。结果显示脐带血ＣＤ_３~＋、ＣＤ_８~＋细胞百分率较成人外周血低（Ｐ＜０．００１），脐血淋巴细胞转化率低。提示进行脐血移植导致移植物抗宿主病（ＧＶＨＤ）的发生率和反应程度均较成人低。
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| 关 键 词： | 脐血；T细胞亚群；造血干细胞 |
The Cell - Immunoreactivity in Cord Blood Compared with That in Adult Veinal Blood |
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| Li Jianrong et al. The Cell - Immunoreactivity in Cord Blood Compared with That in Adult Veinal Blood[J]. Journal of Dali Medical College, 1996, 0(4) |
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| Authors: | Li Jianrong et al |
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| Affiliation: | Li Jianrong et al |
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| Abstract: | There are many hematopoietic stem cells in cord blood. Cord blood transplantation can be used to treat some malignant tumors. By using indirect immuno-fluorescence and lymphocyte transformation test, T lymphocytes subsets and the rete of lymphocyte transformation in cord blood are compared with those in adult veinal blood . The results showed that CD3+ and CD8+ cell rate in cord blood is lower than than in adult veinal blood( P<0.01 ) . It is suggested that cord blood transplantation creates less reaction for grift - versus - host disease(GVHD) than adult veinal blood. |
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| Keywords: | Cord blood T lymphocyte subsets Hematopoietic stem cells |
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