| 差示双波长分光光度法测定泰诺口服液中对乙酰氨基酚的含量 |
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| 引用本文： | 王春英 李国义. 差示双波长分光光度法测定泰诺口服液中对乙酰氨基酚的含量[J]. 药物分析杂志, 1998, 18(5): 316-318 |
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| 作者姓名： | 王春英 李国义 |
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| 作者单位： | [1]河北医科大学药物分析教研室 [2]药理教研室 |
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| 摘 要： | 利用差示双波长分光光度法测定泰诺口服液中对乙酰氨基酚的含量，测定波长为２３２ｎｍ和２６８ｎｍ，利用振幅值为定量信息，可以消除红色背景和辅料的影响。测得回收率为９８９２％～１０２％，ＲＳＤ均小于０４０％。本法与酸水解后重氮化法测定结果比较，无显著性差异
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| 关 键 词： | 差示双波长 分光光度法 对乙酰氨基酚 泰诺 |
Assay of Acetaminophen in Oral Liquid of Tylenol by Double Wavelength-Differential Spectrophotometry |
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| Wang Chunying,Li Guoyi,Zhang Lantong,Wang Qiao,Zhang Aihua and Zhou Yuemian. Assay of Acetaminophen in Oral Liquid of Tylenol by Double Wavelength-Differential Spectrophotometry[J]. Chinese Journal of Pharmaceutical Analysis, 1998, 18(5): 316-318 |
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| Authors: | Wang Chunying Li Guoyi Zhang Lantong Wang Qiao Zhang Aihua Zhou Yuemian |
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| Abstract: | Assay of acetaminophen in oral liquid of Tylenol was reported by double wavelength-differential spectrophotometry in this paper.The wavelengths were adopted 232 nm and 268 nm to provide quantititative information and to eliminate the interference of red colour and excipients.The average recovery and relative standard deviation were satisfactory.The results showed no significant difference in comparison with diazotization titration method. |
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| Keywords: | double wavelength-differential spectrophotometry acetaminophen assay |
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