231例男性青年阻塞性睡眠呼吸暂停低通气综合征患者的睡眠监测及相关分析

目的:分析男性青年阻塞性睡眠呼吸暂停低通气综合征OSAHS患者整夜多导睡眠监测PSG的特点。方法:对我院睡眠医学中心诊断的231例男性青年OSAHS患者的整夜PSG资料进行回顾性分析,对患者的一般情况、呼吸暂停和低通气情况、氧减饱和情况、睡眠结构以及各指标间可能的相关关系进行统计分析。结果:该组OSAHS患者超重率93.07%,肥胖率为75.76%。中位呼吸暂停低通气指数AHI为40.1次/h,AHI>40者占51.95%。中位夜间最低血氧饱和度LSaO2为70%,LSaO265%～<85%占45.45%,<65%者占40.69%。血氧饱和度<90%、<85%、<80%分别占监测总时间的百分比(TS90、TS85、TS80)为20.75%、4.53%、1.66%。快动眼相REM睡眠时间占(17.00±7.45)%,非快动眼相(NREM)睡眠时间占(82.96±7.40)%。AHI除与LSaO2、平均夜间血氧饱和度MSaO2呈负相关,与其他指标均呈正相关,其中与氧减饱和指数ODI、每小时氧减时间(简称氧减/h)相关性强。体重指数BMI与LSaO2、MSaO2呈负相关,与AHI、ODI、最大氧减幅度LDD呈正相关。LSaO2与呼吸暂停最长时间、低通气最长时间、TS90、TS85、TS80均呈负相关。结论:男性青年OSAHS患者超重肥胖率高,存在睡眠结构紊乱。

Monitoring Results and Correlation Analysis of Polysomnography in 231 Cases of Young Male Patients with Obstructive Sleep Apnea Hypopnea Syndrome

Objective: To analyze the characteristics of polysomnography in the young male patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods: Monitoring results of polysomnography(PSG) from 231 young male OSAHS patients were analyzed to learn relationship among the general conditions,apnea and hypopnea events,oxygen reduction and sleep architecture.Results: The rate of overweight and obesity accounted for 93.07% and 75.76%,respectively.The median AHI and LSaO2 were 40.1 times/h and 70%,respectively;the patients with AHI over 40 accounted for 51.95%;LSaO2 between 65% and <85% accounted for 45.45% and with LSaO2 lower than 65% accounted for 40.69%.The percent of the total time with oxygen saturation level<90%,<85%,<80%(TS90,TS85,TS80) accounted for 20.75%,4.53%,1.66%,respectively.REM sleep time was(17.00±7.45)%,and non-REM(NREM) sleep time was(82.96±7.40)%.AHI was negatively correlated with LSaO2 and MSaO2,while it was positively correlated with the others,and had high correlation with ODI and the time of oxygen desaturation in one hour.BMI was negatively correlated with LSaO2 and MSaO2,while it was positively correlated with AHI,ODI,the largest oxygen desaturation degree(LDD).LSaO2 was negatively correlated with LA,LH,TS90,TS85,TS80.Conclusion: The young male patients with OSAHS have high overweight and obesity rate and manifest obvious disorder of sleep structural.