阴道镜在诊断宫颈上皮内瘤变中的筛查作用

目的探讨阴道镜检查在诊断宫颈上皮内瘤变中的初筛作用。方法随机抽取我院妇科门诊病人,2009年月1月～2011年12月共458例,因宫颈细胞学异常者,进行阴道镜检查及定位活检,以组织学诊断为标准进行确诊对比。结果病理检查CINⅡ32例、CINⅢ14例、宫颈癌11例。TCT诊断LISL175例、HISL37例、宫颈癌7例,TCT检测HISL以上病变的敏感度54.38%,特异度96.76%;阴道镜检查结果 CINⅡ27例、CINⅢ9例、宫颈癌10例,阴道镜检查诊断CINⅡ以上病变敏感度为63.16%,特异性为97.50%。两者比较2=0.905,p>0.05。结论阴道镜检查在宫颈上皮内瘤变的筛查中,具有较高的敏感度,特异性高,是一种简便易行、安全价廉的方法,作用确切,值得推广应用。

THE SCREENING VALUE OF COLPOSCOPY IN DIAGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA

Objective To discuss the screening value of colposcopy in the diagnosis of intraepithelial neoplasia.Methods From Jan,2009 to Dec,2011,458 cases with abnormal cervical cytology were selected randomly from gynecology clinic,which received colpocopy and biopsy,in contrast to the diagnosis of histology standard.Results 32 cases were CINⅡ,14 cases were CINⅢ,and 11 cases were cervical cancer according to pathological examination.175 cases were LISL,37 cases were HISL,and 7 cases were cervical cancer by TCT.The sensitivity was 54.38%,and the specificity was 96.76% of TCT in the diagnosis of HISL and so on.27 cases were CINⅡ,9 cases were CINⅢ,and 10 cases were cervical cancer under colposcopy.The sensitivity and specificity of coloscopy for CIN(> = CINⅡ) was 63.16% and 97.5%.It was x2 = 0.905 between two groups(p > 0.05).Conclusion There is high sensitivity and specificity in the screening of colpocopy in the diagnosis of cervical intraepithelial neoplasia.It is simple,convenient,safe and cheap,also exactly effective,which deserve the clinical expansion.