非接触式角膜内皮镜测量正常角膜厚度的研究

目的:采用非接触式角膜内皮镜测量正常人的中央角膜厚度(Central corneal thickness,CCT),并探讨其相关影响因素。方法:采用KONAN非接触式角膜内皮镜测量173例(322只眼)正常眼的中央角膜厚度(CCT),得出正常值范围。同时测量距离角膜正中央3mm处的旁中心角膜厚度(12点、2点、10点、6点方位),并进行角膜内皮细胞检查。所有资料输入计算机后在Windows操作环境下使用SPSS10.0统计软件进行统计分析。结果:非接触式角膜内皮镜测得的正常眼CCT平均值为(554.78 32.61)μm,与性别、眼别无明显相关性,与年龄、角膜内皮细胞密度与平均细胞面积呈非线性相关。距离角膜正中央3mm处,12点方位角膜最厚,6点方位角膜较薄,但均厚于CCT。结论:非接触式角膜内皮镜能准确地测量中央角膜厚度,结果可靠。

Normal Value of the Central Corneal Thickness Measured by Non-contact Specular Microscope

PURPOSE: To get the normal value of the central corneal thickness (CCT) measured by non-contact specular microscope and to approach relatively influenced factor from different aspects. METHOD: The CCT was determined by the KONAN non-contact specular microscope. 173 normal subjects (322 eyes) were measured to get a normal value of the CCT. In the meantime, the para-central corneal thickness (12 o'clock, 2 o'clock, 10 o'clock, 6 o'clock) were measured and the corneal endothelial cell was analyzed in using the same machine. The statistical analysis was performed in using PC SPSS version 10.0 under windows system. RESULT: Measured by the non-contact specular microscope, the mean value of the CCT in normal eyes is (554.78+/-32.61), microm. There was no significant difference between right eyes and left eyes, and between male and female. There is no linear correlation between age, density and average area of the corneal endothelium cell and the CCT. The peripherial corneal thickness is thicker than the CCT. Among the peripherial corneal thickness, the thickest part is in the position of 12 o'clock,while the thinnest part is in the position of 6 o'clock. CONCLUSION: The CCT can be accurately measured by non-contact specular microscope. The measured value is reliable.