血凝酶封堵针道预防肺穿刺活检并发症

目的 观察血凝酶封堵针道预防肺穿刺活检并发症的价值。方法 回顾性分析155例接受CT引导下经皮肺穿刺活检的单发肺结节患者，将其分为观察组（n=78，退针时以血凝酶封堵针道）与对照组（n=77，直接退针）；完成操作后即刻复查CT，比较组间肺出血级别及肺压缩面积占比。结果 对155例均成功取材，于其中150例（150/155，96.77%）获得明确病理诊断。观察组20例（20/78，25.64%）、对照组38例（38/77，49.35%）发生高级别出血；观察组18例（18/78，23.08%）发生气胸、肺压缩面积占比为0（0，0），对照组31例（31/77，40.26%）发生气胸、压缩面积占比为0（0，0.76%）；观察组均低于对照组（P均＜0.05）。结论 肺穿刺活检后退针时以血凝酶封堵针道可降低出血及气胸风险。

Hemagglutinin occlusion of needle passage for preventing complications of pulmonary puncture biopsy

Objective To observe the value of hemagglutinin occlusion of needle passage for preventing complications of pulmonary puncture biopsy. Methods Data of 155 patients with single pulmonary nodule who underwent CT-guided percutaneous lung puncture biopsy were retrospectively analyzed. The patients were divided into observation group （n=78， injected hemagglutinin when withdrawing the needle） and control group （n=77， directly withdrawn the needle）. Chest CT examination was performed immediately after completion of the procedure. Pulmonary hemorrhage grades were evaluated， and the proportions of compressed lung area were measured and compared between groups. Results Puncture and sampling were successfully performed in all 155 patients， and definite pathological diagnose was acquired in 150 cases （150/155， 96.77%）. High-grade hemorrhage was detected in 20 cases （20/78， 25.64%） of observation group and 38 cases （38/77， 49.35%） of control group， while pneumothorax was noticed in 18 cases （18/78， 23.08%） with lung compression area proportion of （0 ［0， 0］） in observation group， and in 31 cases （31/77， 40.26%） with lung compression area proportion of 0 ［0， 0.76%］ in control group， respectively， in observation group were better than in control group （all P＜0.05）. Conclusion Occlusion needle passage when withdrawing needle with hemagglutinin after pulmonary puncture biopsy could reduce the risk of hemorrhage and pneumothorax.