老年甲状腺功能亢进患者情绪障碍和生活质量调查

目的 对老年甲状腺功能亢进患者情绪障碍及生活质量进行调查,并分析影响其生活质量的因素。方法 选择2022年1月至2023年4月湖北文理学院附属医院襄阳市中心医院收治的134例老年甲状腺功能亢进患者。并对其进行甲状腺激素水平检测和问卷调查,包括基础资料、焦虑自评量表(SAS)、抑郁自评量表(SDS)及简明生活质量量表(SF-36)。采用SPSS 26.0软件进行数据分析。根据数据类型,组间比较分别采用t检验及方差分析。采用Pearson相关性分析患者情绪障碍与生活质量的相关性；采用多因素logistic回归分析老年甲状腺功能亢进患者生活质量的影响因素。结果 本次老年甲状腺功能亢进患者SAS得分为(52.97±4.33)分,SDS得分为(54.89±4.68)分,生活质量得分为(65.25±6.39)分。不同受教育程度、居住方式、家庭人均月收入、游离甲状腺素(FT4)和游离三碘甲状腺原氨酸(FT3)水平的老年甲状腺功能亢进患者生活质量得分比较,差异有统计学意义(P<0.05)。Pearson相关性分析显示,老年甲状腺功能亢进患者生活质量得分与SAS、SDS得分均呈负相关性(r=-0.403、-0.361；均P<0.05)。多因素logistic回归分析结果显示,受教育程度、家庭人均月收入、FT3和FT4水平以及SAS和SDS得分是老年甲状腺功能亢进患者生活质量的影响因素(P<0.05)。结论 老年甲状腺功能亢进患者容易发生情绪障碍,生活质量较低,而受教育程度、家庭人均月收入、FT3和FT4水平以及情绪障碍均是影响其生活质量的重要因素。

Emotional disorders and quality of life in elderly patients with hyperthyroidism

Objective To investigate emotional disorders and quality of life (QOL) in elderly patients with hyperthyroidism, and analyze the factors influencing their quality of life. Methods A total of 134 elderly patients with hyperthyroidism admitted to our hospital from January 2022 to April 2023 were enrolled in this study. Their thyroid hormone levels were measured, and questionnaires were conducted, including demographic information, self-assessment anxiety scale (SAS), self-assessment depression scale (SDS), and 36-item short-form health survey (SF-36). SPSS statistics 26.0 was used for statistical analysis. Data comparison between two groups was perfomed using t test, or analysis of variance depending on data type. Pearson correlation analysis was used to examine the correlation between emotional disorders and quality of life in patients. Multiple logistic regression analysis was used to investigate the influencing factors of quality of life in elderly patients with hyperthyroidism. Results The SAS, SDS and QOL scores were (52.97±4.33), (54.89±4.68) and (5.25±6.39) points, respectively, in the elderly patients with hyperthyroidism. There were statistically differences in QOL score among these elderly patients with different education levels, living conditions, household per capita monthly income, and free thyroxine (FT4) and free triiodothyronine (FT3) levels (P<0.05). Pearson correlation analysis showed a negative correlation between QOL score and SAS and SDS scores in them (r=-0.403, -0.361; both P<0.05). Multivariate logistic regression analysis indicated that education level, household per capita monthly income, FT3 and FT4 levels, as well as SAS and SDS scores were influencing factors for QOL in elderly patients with hyperthyroidism (P<0.05). Conclusion Elderly patients with hyperthyroidism are prone to emotional disorders and have poor QOL. Education level, household per capita monthly income, FT3 and FT4 levels, as well as emotional disorders are important factors influencing their QOL.