| 嗓音语图频谱分析对帕金森病患者的诊断意义 |
| |
| 引用本文： | 孙永柱,崔鹏程,陈文弦,李贵泽,孙安. 嗓音语图频谱分析对帕金森病患者的诊断意义[J]. 中国组织工程研究与临床康复, 2002, 6(23): 3512-3513 |
| |
| 作者姓名： | 孙永柱 崔鹏程 陈文弦 李贵泽 孙安 |
| |
| 作者单位： | 解放军第四军医大学唐都医院,陕西西安,710038 |
| |
| 摘 要： | 目的研究正常人及帕金森病(Parkinson`sdiseasePD)患者手术前后嗓音的声学特征,探讨语音频谱分析系统在帕金森病的诊断及治疗中的应用价值。方法采用USSA语音频谱分析系统对30例正常成人及54例喉病患者发持续元音犤a:犦时的声音信号进行检测,分析帕金森病的基频、共振峰、频率微扰、振幅微扰和谐噪比,同时观察语图谐波、共振峰及噪声成分特征及变化规律。结果帕金森病F0,F1,F2,F3值与对照组及术后比较,频率均值差异有显著性意义(P<0.05,P<0.01)。PD组手术前APQ值、FPQ值增高,H/N值下降,与正常组及术后对比差异有显著性意义(P<0.05)。PD患者语图表现谐波及共振峰不规则,噪声成分增加。结论计算机语音频谱分析系统可作为检测PD的有效客观指标。
|
| 关 键 词： | 帕金森病 嗓音 频谱分析 声图 |
| 文章编号： | 1671-5926(2002)23-3512-02 |
| 修稿时间： | 2002-07-15 |
Clinical signification of voice spectrum analysis in normal adults and Parkinson''''s diseases |
| |
| SUN Yong zhu,CUI Peng cheng,CHEN Wen xian,et al.. Clinical signification of voice spectrum analysis in normal adults and Parkinson''''s diseases[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(23): 3512-3513 |
| |
| Authors: | SUN Yong zhu CUI Peng cheng CHEN Wen xian et al. |
| |
| Affiliation: | SUN Yong zhu,CUI Peng cheng,CHEN Wen xian,et al.Department of Otorhinolaryngology,Tandu Hospital,Fourth Military Medical University,Xi'an 710038,China |
| |
| Abstract: | Objectives To investigate the value of the universal signal spectrum analysis system in the diagnosis of Parkinson's disease.Methods Spectrogram and sonogram were analyzed with the system in patients of 54 Parkinson's diseases and 30 normal adults. Results The fundamental frequency(F0),first,second and third formant(F1,F2,F3), Frequency perturbation quotient (FPQ), amplitude perturbation quotient (APQ)and Harmonics to noise ratio(H/N) were found significantly different from the normal control group and postoperative group. The sonogram showed decrease or loss of harmonic waves and formants and increase of noise in middle and high frequencies.Conclusion Both acoustic parameters and sonogram could provide objective grounds for clinical voice evaluation. |
| |
| Keywords: | Parkinson's disease voice spectrum analysis sonogram |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
