| 急性髓系细胞白血病bcl-2表达水平与预后的关系 |
| |
| 引用本文： | 柳金,曹萍,齐振华.急性髓系细胞白血病bcl-2表达水平与预后的关系[J].中南大学学报(医学版),2000,25(3):265-266. |
| |
| 作者姓名： | 柳金 曹萍 齐振华 |
| |
| 作者单位： | 深圳市中心医院血液内科 |
| |
| 摘 要： | 采用免疫组化方法测定 5 8例急性髓系细胞白血病患者抗凋亡基因bcl 2蛋白表达水平 ,分析bcl 2基因与临床预后关系。结果表明 ,高表达bcl 2患者 ,化疗反应差 ,预后不良。提示bcl 2表达水平可作为判断急性髓系细胞白血病预后的重要指标之一。
|
| 关 键 词： | 白血病 髓细胞性 急性 细胞凋亡 预后 |
Relationship between the expression of bcl-2 apoptosis and acute myelogenous leukemia prognosis |
| |
| LIU Jin,CAO Ping,QI Zhenhua.Relationship between the expression of bcl-2 apoptosis and acute myelogenous leukemia prognosis[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2000,25(3):265-266. |
| |
| Authors: | LIU Jin CAO Ping QI Zhenhua |
| |
| Affiliation: | Department of Hematology, Xiangya Hospital, Hunan Medical University(Changsha 410008) |
| |
| Abstract: | In order to check the antiapoptosis gene bcl2 protein expression in 58 AML patients we used the immunohistochemied method, and analyse the relationship between bcl2 protein and prognosis of AML. The result showed that the high expression of bcl2 protein was related to poor clinical prognosis of AML. This shows that the expression of bcl2 gene can serve as an index for the prognosis of AML. |
| |
| Keywords: | Apoptosis leukemia myelogenous acute prognosis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中南大学学报(医学版)》浏览原始摘要信息 |
|
点击此处可从《中南大学学报(医学版)》下载全文 |
