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Pseudomembranous Colitis with Recurring Diarrhoea and Prolonged Persistence of Clostridium Difficile in A 10-Year-Old Girl
Authors:T. VESIKARI,M. MAKI,MÄ  IJA BAER,P. GRÖ  NROOS
Affiliation:Department of Clinical Sciences, University of Tampere, Tampere, Finland;Department of Paediatrics, Tampere University Central Hospital, Tampere, Finland;Department of Microbiology, Tampere University Central Hospital, Tampere, Finland
Abstract:ABSTRACT. A 10-year-old girl developed, after treatment with amyxocillin, a clinically and sigmoidoscopi-cally apparent pseudomembranous colitis with positive Clostridium difficile stool culture. Treatment with vancomycin resulted in rapid clinical cure, but there was a relapse of diarrhoea and reappearance of C. difficile , with no pseudomembranous colitis, within one month. Clinical symptoms subsided spontaneously but C. difficile persisted for 2 more months in the stools. This case reflects three different aspects of C. difficile infection in one child: pseudomembranous colitis, ordinary diarrhoea, and symptomless carrier state.
Keywords:Clostridium difficile    pseudomembranous colitis    diarrhoea    antibiotic-associated-diarrhoea
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