实时超声弹性成像对桥本甲状腺炎的应用价值研究

目的：探讨实时超声弹性成像在桥本甲状腺炎（HT）诊断中的应用价值。方法：对175例临床确诊为HT的患者进行常规超声及实时超声弹性成像检查,根据二维声像图特征分为回声不均型、斑片型、弥漫型及结节型,并与30例健康者作对照,分析正常对照组及各型HT弹性图分级及应变率比值。结果：HT弹性图分级四型之间存在差异（P〈0.05）,回声不均型多为0、1级,斑片型以1、2级为主,弥漫型以2、3级为主,结节型以3级为主。回声不均型与正常对照组之间弹性分级、应变率比值差别无统计学意义（P〉0.05）,四型HT之间弹性分级、应变率比值差异有统计学意义（P〈0.05）,且从回声不均型到结节型,分级程度逐次增高,应变率比值依次增大（P〈0.05）。结论：实时超声弹性成像能够估测不同类型HT甲状腺实质硬度的差别,为HT常规超声诊断提供了辅助信息。

Real-time elastosonography in diagnosis of Hashimoto thyroiditis

Objective: To investigate the diagnostic value of real-time ultrasound elastosonography(EU)in diagnosis of Hashimoto thyroiditis(HT).Methods: One hundred and seventy-five cases clinically diagnosed as HT under went traditional ultrasound and elastosonography.The patients were classified into four types including unevenness pattern,focal hypoechoic pattern,asystematic hypoechoic pattern and nodular pattern.Thirty healthy volunteers were enrolled as control group.Thyroid elastic parameters(elastic image pattern and strain ratio) were recorded and analyzed.Results: There were significant differences in elastic image pattern between four HT groups(P<0.05).The unevenness pattern mainly had grade 0 and grade 1,focal hypoechoic pattern mainly had grade 1 and grade 2,asystematic hypoechoic pattern mainly had grade 2 and grade 3 and nodular pattern mainly had grade 3,and elastic image pattern were increased gradually from unevenness pattern to nodular pattern(P<0.05).There were no significant differences between control and unevenness pattern in elastic image pattern and strain ratio(P>0.05).There were significant differences between four HT groups(P<0.05)in strain ratio,and were increased gradually from unevenness pattern to nodular pattern(P<0.05).Conclusion: Real-time ultrasound elastography can estimate stiffness differences in different partern HT,and is helpfuI for the diagnosis of HT.