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Chromoblastomycosis Associated with Bone and Central Nervous Involvement System in an Immunocompetent Child Caused by Exophiala Spinifera |
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| Authors: | Sahana M Srinivas Vykuntaraju K Gowda S Mahantesh Rajeshwari Mannapur Sanjay K Shivappa |
| Affiliation: | From the Department of Pediatric Dermatology, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India;1Department of Pediatric Neurology, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India;2Department of Microbiology, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India;3Department of Pediatrics, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India |
| Abstract: | Chromoblastomycosis is a chronic granulomatous infection of the skin and subcutaneous tissue caused by specific group of dematiaceous fungi. The infection results from traumatic injury and is seen more commonly on feet and lower legs. It is rarely seen in children and metastatic spread to other systems is exceptionally rare. We report a 12-year-old immunocompetent male child diagnosed with chromoblastomycosis on the lower leg, who in a span of few months developed osteomyelitis and left hemiparesis. Fungal culture showed growth of Exophiala spinifera. Child showed good improvement with voriconazole and itraconazole after 1 year of treatment. Skin lesions healed with minimal scarring and his power improved. |
| Keywords: | Chromoblastomycosis Exophiala spinifera fungal granuloma fungal osteomyelitis voriconazole |