| 亮氨酸氨基肽酶在HBV慢性肝病鉴别诊断中的意义 |
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| 引用本文： | 宋文慧. 亮氨酸氨基肽酶在HBV慢性肝病鉴别诊断中的意义[J]. 江西医学检验, 2008, 26(1): 13-14 |
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| 作者姓名： | 宋文慧 |
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| 作者单位： | 宋文慧（315100,浙江省宁波市鄞州区第二医院检验科） |
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| 摘 要： | 目的检测HBV慢性肝病患者血清中的亮氨酸氨基肽酶（leucine aminopeptidase，LAP）活性变化，探讨其临床意义。方法采用速率法检测HBV慢性肝病患者血清LAP的活性,选择110例健康献血员做对照，对118例HBV慢性肝病患者（慢性肝炎组、代偿期肝炎肝硬化组、失代偿期肝炎肝硬化组）血清中LAP活性进行了测定。结果在HBV慢性肝病组中失代偿期肝炎肝硬化组患者血清中LAP活性升高最明显，与对照组和其他肝病组比较均有显著性差异（P〈0．01）：代偿期肝炎肝硬化组LAP活性与慢性肝炎组比较有差异（P〈0．05），与对照组比较有显著性差异（P〈0．01）；慢性肝炎组与对照组比较有差异（P〈0．0S）。结论LAP活性在HBV慢性肝病中普遍升高，但失代偿期肝炎肝硬化患者最高，此可作为HBV慢性肝病鉴别诊断的一项初步指标。
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| 关 键 词： | 亮氨酸氨基肽酶 慢性肝病 HBV感染 鉴别诊断 |
| 文章编号： | 1674-1129(2008)01-0013-02 |
The clinical significance of leucine aminopeptidse in the diagnosis of patients with chronic liver diseases infected HBV |
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| Song Wenhui. Yinzhou Second Hospital,Nibong ,China. The clinical significance of leucine aminopeptidse in the diagnosis of patients with chronic liver diseases infected HBV[J]. Jiangxi Journal of Medical Laboratory Sciences, 2008, 26(1): 13-14 |
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| Authors: | Song Wenhui. Yinzhou Second Hospital Nibong China |
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| Affiliation: | Song Wenhui. Yinzhou Second Hospital,Nibong 315100,China |
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| Abstract: | Objective To study the clinical significance of serum leucine aminopeptidse(LAP) activity in patients with chronic liver diseases infected HBV. Methods The kinetic method was employed to examine the the serum LAP activity in 136 patients and 110 healthy controls. Results The LAP level in decompensated liver cirrhosis group was higher than those in other liver disease groups and control group,and showed significant differences in the decompensated liver cirrhosis group compared with other groups (P<0.01); Th... |
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| Keywords: | Leucine aminopeptidase Chronic liver diseases HBV infection Differential diagnosis |
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