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HMME-PDT治疗鲜红斑痣238例临床疗效分析
引用本文:王开,顾瑛,刘凡光,梁洁,潘玉明,曾晶,童新元. HMME-PDT治疗鲜红斑痣238例临床疗效分析[J]. 中国美容医学, 2003, 12(5): 476-478
作者姓名:王开  顾瑛  刘凡光  梁洁  潘玉明  曾晶  童新元
作者单位:1. 解放军总医院理疗科,北京市,100853
2. 解放军总医院激光科
3. 军医进修学院数理统计室
摘    要:目的:对鲜红斑痣患者HMME-PDT治疗后的临床疗效进行分析并探讨其有关影响因素、方法:对238例鲜红斑痣患者共计296个红斑区给予HMME-PDT治疗。观察治疗区术后反应并判定其疗效。结果:治疗后红斑区出现水肿、结痴和脱痂等光敏反应。治疗总有效率达100%,其中疗效达Ⅰ级者占8.8%(26/296),Ⅱ级者占36.5%(108/296),Ⅲ级者占48.0%(142/296),Ⅳ级者占6.8%(20/296)。粉红型患者Ⅰ级疗效率(26.3%)明显高于紫红型(8.8%)和增厚型(5.9%)、结论:HMME-PDT治疗鲜红斑痣效果明显,安全可靠。

关 键 词:HMME-PDT 治疗 鲜红斑痣 临床疗效 光动力疗法 血卟啉单甲醚
文章编号:1008-6455(2003)05-0476-02
修稿时间:2003-04-10

Clinical analysis of 238 cases of port wine stains patients treated by HMME-PDT
WANG Kai,GU Ying,LIU Fan -guang,LIANG Jie,PAN Yu -ming,ZENG Jing and TONG Xing-yuan. Clinical analysis of 238 cases of port wine stains patients treated by HMME-PDT[J]. Chinese Journal of Aesthetic Medicine, 2003, 12(5): 476-478
Authors:WANG Kai  GU Ying  LIU Fan -guang  LIANG Jie  PAN Yu -ming  ZENG Jing  TONG Xing-yuan
Abstract:Objective To observe the responses and evaluate the effect of the treated area of Port Wine Stains patients following HMME - Photodynamic Therapy. Methods 238 patients with 296 lesions were treated by HMME -PDT. The treated skin responses were observed and the therapeutic effect was evaluated. Results Swelling and scabbing were usually observed within two weeks after treatment. Total effective rate is 100%, including 8.8% grade I, 36.5%grade, 48.0% grate II and 6.8% grade IV.The grade I effective rate of patients with pink lesions is significantly higher than those who with purple or proliferation lesions. Conclusion HMME-PDT is an effective and safe modality for port wine stain treatment.
Keywords:photodynamic therapy  port wine stains  hematoporphyrin monomethyl ether
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