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Effects of experimental hyperlipoproteinemia on the canine eye |
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| Authors: | D H Slatter A W Nelson J M Stringer |
| Affiliation: | 1. Surgical Laboratory, Department of Clinical Sciences, College of Veterinary Medicine, Colorado State University, Fort Collins, Colorado 80521, U.S.A.;2. Department of Anatomy, College of Veterinary Medicine, Colorado State University, Fort Collins, Colorado 80521, U.S.A. |
| Abstract: | Hyperlipoproteinemia was induced in dogs of different ages. No effects were observed in the fundus. Lipid was deposited in peripheral cornea in proportion to the level of plasma cholesterol in three of 12 eyes. Extensive lipid deposition was observed in the anterior peripheral corneal stroma. In electron micrographs, intracytoplasmic membrane-bound vacuoles were seen in keratocytes and crystalline spaces were present in corneal stroma. |
| Keywords: | canine hypercholesterolemia eye retina cornea keratopathy atherosclerosis hyperlipoproteinemia |
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