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肺小结节定位研究进展
引用本文:吕璐,严小鹏,张至轩,宋雅莉,李双燕,付军科,马锋,吕毅,张勇.肺小结节定位研究进展[J].国际外科学杂志,2020(3):197-201,F0004.
作者姓名:吕璐  严小鹏  张至轩  宋雅莉  李双燕  付军科  马锋  吕毅  张勇
作者单位:西安交通大学第一附属医院胸外科;西安交通大学第一附属医院肝胆外科;西安交通大学启德书院;西安交通大学第一附属医院精准外科与再生医学国家地方联合工程研究中心
基金项目:陕西省重点研发计划(2019SF-014);白求恩公益基金项目(HZB-20181119-070);陕西省卫生计生委计划项目(2018D056);西安交通大学大学生创新训练项目(SJ201910698098)。
摘    要:随着CT技术的发展和体检的普及,肺部小结节的检出率不断提高。其中部分肺小结节不能排除恶性肿瘤的可能,治疗首选手术切除。因此,如何在术中对肺小结节精确定位、并在最大限度保护肺功能的前提下精准切除结节,是胸外科医师面临的重要课题。目前,肺部小结节术前辅助定位的核心是置入标志物,临床常用的定位方法主要有带钩金属丝定位法、微弹簧圈定位法、亚甲蓝穿刺注射定位法以及生物胶定位法等。本文简要综述现有定位方法的发展现状、适用范围及优缺点等,为临床应用及后续研究提供参考。

关 键 词:  孤立性肺结节  多发性肺结节

Progress in localization of pulmonary nodules
Lyu Lu,Yan Xiaopeng,Zhang Zhixuan,Song Yali,Li Shuangyan,Fu Junke,Ma Feng,Lyu Yi,Zhang Yong.Progress in localization of pulmonary nodules[J].International Journal of Surgery,2020(3):197-201,F0004.
Authors:Lyu Lu  Yan Xiaopeng  Zhang Zhixuan  Song Yali  Li Shuangyan  Fu Junke  Ma Feng  Lyu Yi  Zhang Yong
Institution:(Department of Thoracic Surgery,the First Affiliated Hospital of Xi′an Jiaotong University,Xi′an,710061,China;Department of Hepatobiliary Surgery,the First Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710061,China;Qide College,Xi′an Jiaotong University,Xi′an 710061,China;National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine,the First Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710061,China)
Abstract:With the development of CT and the popularization of health examination,the detection rate of small pulmonary nodules has been improved.Some small pulmonary nodules could be malignant nodules.Surgical resection is the preferred treatment.Therefore,it is an important task for thoracic surgeons to accurately locate pulmonary nodules during surgery and remove nodules accurately on the premise of maximum protection of lung function.At present,the core of preoperative auxiliary localization of pulmonary nodules is the implantation of markers.The commonly used clinical localization methods include hook wire localization,microcoil localization,methylene blue puncture injection localization and biological glue localization.In this paper,the development status,application scope,advantages and disadvantages of existing localization methods are briefly reviewed,which can provide references for clinical application and follow-up research.
Keywords:Lung  Solitary pulmonary nodule  Multiple pulmonary nodules
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