综合护理干预对经皮冠状动脉介入术联合替罗非班治疗急性ST段抬高型心肌梗死患者预后的影响

目的 探讨替罗非班应用于急性ST段抬高型心肌梗死介入治疗患者的临床疗效及护理体会.方法 选择经皮冠状动脉介入术（PCI）联合替罗非班治疗的急性ST段抬高型心肌梗死患者80例,按照随机数字法分为对照组和观察组,每组各40例,对照组采用常规护理,观察组实施综合护理干预,比较两组患者血流灌注心肌梗死溶栓试验（TIMI）分级情况、心电图ST段回落及并发症情况.结果 观察组治疗后血流灌注有效率为95.0％,明显高于对照组（65.0％）,差异有统计学意义（x2=11.25,P＜0.05）.观察组ST段回落率为85.0％,对照组为65.0％,两组比较差异有统计学意义（x2=4.27,P＜0.05）；观察组并发症发生率（7.5％）明显低于对照组（5.0％）,两组比较差异有统计学意义（x2=4.50,P＜0.05）.结论 对于急性ST段抬高型心肌梗死介入治疗患者,围术期给予有效的综合护理干预,能够明显提高临床疗效,降低并发症的发生率,值得临床推广.

Effect of comprehensive nursing intervention on clinical efficacy of the combination of PCI and tirofiban in patients with acute STEMI

Objective To investigate and discuss the clinical efficacy and nursing experience of the combination of tirofiban and percutaneous coronary intervention （PCI） in patients with acute ST-segment elevation myocardial infarction （STEMI）.Methods A total of 80 patients with acute STEMI who had undergone the combination of PCI and tirofiban in our hospital were selected and randomly divided into the control group （routine nursing） and the observation group （comprehensive nursing intervention）,with 40 patients in each group.The blood flow perfusion thrombolysis in myocardial infarction trial （TIMI）classification,the resolution of ST-segment,and complications in the two groups were observed and compared.Results The effect rate of blood perfusion in the observation group was significantly higher that in the control group （95.0％ vs 65.0％）,and the difference was statistically significant （x2 =11.25,P ＜ 0.05）.The resolution rate of ST segment obviously increased in the observation group compared with the control group （85.0％ vs 65.0％）,and the difference was statistically significant （x2 =4.27,P ＜ 0.05）.The incidence of complications was significantly decreased in the observation group compared with the control group （7.5％ vs 25.0％）,with statistical difference between the two groups （x2 =4.50,P ＜ 0.05）.Conclusions For patients with acute STEMI who had undergone the combination of PCI,the effective application of comprehensive nursing intervention in the perioperative period can significantly improve the clinical efficacy and reduce the incidence of complications,which should be worthy of clinical promotion.