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ECG gated thallium 201 myocardial images: Value in detecting multivessel disease in patients on anti anginal therapy 1–3 months after myocardial infarction
Authors:Héric Valette  Michel H. Bourguignon  Dominique Le Guludec  Pascal Merlet  Patrick J. Dove  Jean-Pierre Kiger  Michel Slama  Gilbert Motte  Claude Raynaud  Andre Syrota
Affiliation:1. Laboratoire d’Explorations Cardiovasculaires, H?pital de Bicetre, Kremlin-Bicêtre, Cedex, France
3. Departement de Biologie, CEA H?pital d’Orsay, Orsay, France
4. Service de Cardiologie, H?pital de Bligny, Briis-s/Forges, France
5. Service de Cardiologie, H?pital Antoine Béclère, Clamart, France
Abstract:ECG gated201T1 scintigraphy was compared to non gated images for detecting 2–3 vessel disease 1–3 months after a first uncomplicated myocardial infarction. In all, 111 patients on anti anginal treatment underwent coronary arteriography and stress thallium imaging; 39 showed single vessel disease (SVD), and 72 multivessel disease (MVD). Sensitivity of black and white analog images was 82% for SVD and 8% for MVD. Sensitivity of computerized colored static images was 87% for SVD and 33% for MVD. For gated images, sensitivity was 100% and 92% in patients with SVD and MVD respectively. Specificity for detecting MVD was 95% for black and white images, 77% for computerized colored static images, and 69% for ECG gated images. Thus, ECG gated exercise201TL scintigraphy is useful for predicting the extent of coronary artery disease 1-3 months after myocardial infarction in patients on anti anginal therapy.
Keywords:201Tl myocardial scintigraphy  ECG gating  Coronary artery disease  Myocardial infarction
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