| 抗精神病药对精神分裂症患者认知功能的影响 |
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| 引用本文： | 张立勇,陈云芳. 抗精神病药对精神分裂症患者认知功能的影响[J]. 临床精神医学杂志, 2005, 15(1): 21-22 |
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| 作者姓名： | 张立勇 陈云芳 |
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| 作者单位： | 050081,石家庄,武警河北总队医院精神卫生中心;050081,石家庄,武警河北总队医院精神卫生中心 |
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| 摘 要： | 目的：比较利培酮和氯氮平对精神分裂症患者认知功能的影响。方法：对58例精神分裂症患者随机分成两组，分别给予利培酮、氯氮平治疗8周。治疗前和治疗8周末分别进行简明精神病评定量表(BPRS)、韦氏成人记忆量表修订本(WMS-RC)、威斯康星卡片分类测验(WCST)和数字划销测验(CT)评定，比较利培酮和氯氮平对精神分裂症患者认知功能的影响。结果：两组8周后，各项检查项目均有显著好转。结论：利培酮和氯氮平均能改善精神分裂症患者的认知功能。
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| 关 键 词： | 利培酮 氯氮平 精神分裂症 认知功能 |
| 文章编号： | 1005-3220(2005)01-0021-02 |
| 修稿时间： | 2004-10-12 |
Effects of antipsychotic drug on cognitive function in schizophrenia patients |
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| ZHANG Li-yong,CHEN Yun-fang. Effects of antipsychotic drug on cognitive function in schizophrenia patients[J]. Journal of Clinical Psychological Medicine, 2005, 15(1): 21-22 |
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| Authors: | ZHANG Li-yong CHEN Yun-fang |
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| Affiliation: | ZHANG Li-yong,CHEN Yun-fang.Mental Health Center,Heibei Provincial Corps Hospital,Armed Police Forces,Shijiazhuang 050081,China |
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| Abstract: | Objective:To compare the effects between risperidone and clozapine on cognitive function in schizophrenics. Method:Fifty-eight cases of schizophrenia patients were randomly divided into two groups and treated with resperidone or clozapine for 8 weeks.The effects on cognitive function of schizophrenia patients were evaluated separately with brief psychiatric rating scale (BPRS),WMS-RC,WCST and CT before and after treatment. Results:The total score of every test was significantly improved after treatment with risperidone or clozapine, but no significant differences were found between two groups. Conclusion:Both risperidone and clozapine can improve the cognitive function in schizophrenic patients. |
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| Keywords: | risperidone clozapine schizophrenia cognitive function |
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