经鼻高频通气救治急性肺损伤的临床探讨

对５例急性肺损伤患者（ＡＬＩ）进行经鼻高频通气（ＮＨＦＶ）的临床观察，评价ＮＨＦＶ对该病的治疗价值。观察结果表明：患者经高频通气后，ＰａＯ＿２和ｐＨ明显升高，呼吸和脉搏逐渐恢复，５例患者均存活出院。作者认为：高频通气是治疗急性肺损伤的一种有效的无创性人工通气方法，能纠正低氧血症，改善通气和呼吸困难。可作为早期治疗ＡＬＩ的常规通气治疗方法，减少或避免气管插管或切开，如ＮＨＦＶ通气疗效不显，再改用气管插管或切开，使用其它通气方式治疗。

Acute lung injury treatetl by nasal high frequency ven-tilation:clinical study

We carried out a prospective trial of nasal high fre-quency ventilation(NHFV) in 5 patients with acute lunginjury(ALI)due to severe trauma or sepsis to investigatethe role of NHFV. After NHFV there was a significantrise in PaO_2 and pH(P<0.01 )and a gradual recovery ofrespiratory and pulse rates. All five patients survived andwas discharged. We conclude that NHFV may be used asan effective non-invasive ventilatorv methdfor treat-ing patients with ALI. NHFV can be used to correct hy-poxemia , improve ventilation and relieve dyspnea. Henceit may be considered as a regular ventilatory therapy forthe early treatment of ALI in order to lessen or avoid en-dotracheal intubation and tracheotomy. If the therapeuticeffectiveness is not significant with the use of NHFV,endotracheal intubation or tracheotomy, or other medesof ventilation can be employed.