| 小儿血清苗勒抑制物质水平变化及其临床意义 |
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| 引用本文： | 徐伟珏,朱鋐达,许恩,张志方,钱梦英,夏毓华,龚代贤,严肃.小儿血清苗勒抑制物质水平变化及其临床意义[J].中华内分泌代谢杂志,2004,20(3):246-247. |
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| 作者姓名： | 徐伟珏 朱鋐达 许恩 张志方 钱梦英 夏毓华 龚代贤 严肃 |
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| 作者单位： | 1. 200025 上海第二医科大学附属瑞金医院儿外科
2. 上海市内分泌代谢病研究所,上海市内分泌代谢病临床医学中心 |
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| 基金项目： | 上海市科委资助课题 (0 0 4 1 1 90 87) |
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| 摘 要： | 通过测定非泌尿生殖系统疾病及隐睾患者的血清苗勒抑制物质 (MIS)值 ,观察年龄与MIS的相关性。结果男性非泌尿生殖系统疾病患儿血清MIS值随年龄增长而下降 ,女性儿童血清MIS值明显低于男性 ,且不随年龄变化 ,青春发育前期隐睾儿童血清的MIS值高于同龄儿。MIS测定可以作为反映隐睾患儿的睾丸功能及成熟程度的指标
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| 关 键 词： | 抗苗氏管物质(苗勒抑制物质) 隐睾 睾酮 |
| 修稿时间： | 2003年11月26 |
Change of serum mullerian inhibiting substance level and its clinical significance in children |
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| XU Wei-jue ,ZHU Hong-da,XU En,ZHANG Zhi-fang,QIAN Meng-ying,XIA Yue-hua,GONG Dai-xian,YAN Su.Change of serum mullerian inhibiting substance level and its clinical significance in children[J].Chinese Journal of Endocrinology and Metabolism,2004,20(3):246-247. |
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| Authors: | XU Wei-jue ZHU Hong-da XU En ZHANG Zhi-fang QIAN Meng-ying XIA Yue-hua GONG Dai-xian YAN Su |
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| Institution: | XU Wei-jue *,ZHU Hong-da,XU En,ZHANG Zhi-fang,QIAN Meng-ying,XIA Yue-hua,GONG Dai-xian,YAN Su. *Department of Pediatric Surgery,Ruijin Hospital,Shanghai Second Medical University,Shanghai 200025 Corresponding author: XU Wei-jue,Email: xu_weijue@hotmail.com |
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| Abstract: | The relationship between mullerian inhibiting substance (MIS) and age in children suffering from non-urogenital disease and cryptorchidism was explored. In patients with non-urogenital disease, MIS level in boys decreased progressively with aging, while that in girls remained unchanged and much lower than that in boys. MIS in boys with cryptorchidism was higher than that in boys of the same age before puberty. MIS may be a useful marker in reflecting testicular growth and function in cryptorchid children. |
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| Keywords: | Anti-Mullerian hormone (Mullerian inhibiting substance) Cryptorchidism Testosterone |
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