| 先心病肺动脉高压肺部显微及超微病变与临床资料对比分析 |
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| 引用本文： | 阮英茆,朱晓东,程显声,张连庄,赵永平,司文学. 先心病肺动脉高压肺部显微及超微病变与临床资料对比分析[J]. 中国循环杂志, 1993, 0(7) |
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| 作者姓名： | 阮英茆 朱晓东 程显声 张连庄 赵永平 司文学 |
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| 作者单位： | 中国医学科学院心血管病研究所、阜外医院病理科(阮英茆，张连庄，赵永平)，中国医学科学院心血管病研究所、阜外医院外科(朱晓东)，中国医学科学院心血管病研究所肺心病研究室、阜外医院肺心病研究室(程显声)，中国医学科学院心血管病研究所、阜外医院病理科(司文学) |
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| 摘 要： | 本文报告先心病肺动脉高压16例的病理(显微及超微)变化与血液动力学及手术效果对照分析。我们发现主要高压性病变在肺小动脉及微细动脉,而不在肺泡气—血屏障。在死亡组(7例)的肺动脉高压肺血管阻力及病理改变比存活组(9例)严重。在死亡组更多见到肺血管血栓形成、丛状病变、肺动脉壁平滑肌细胞增生,肺动脉壁和肺间质的胶原及弹力纤维更增多等。
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| 关 键 词： | 先天性心脏病 肺动脉高压 超微病变 |
CORRELATIVE ANALYSIS OF PULMONARY ULTRASTRUCTURAL CHANGES AND CLINICAL DATA OF CONGENITAL HEART DISEASE WITH PULMONARY HYPERTENSION |
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| Ruan YingMao,Zhu Xiao-Dong,Cheng Xian-Sheng,et al.. CORRELATIVE ANALYSIS OF PULMONARY ULTRASTRUCTURAL CHANGES AND CLINICAL DATA OF CONGENITAL HEART DISEASE WITH PULMONARY HYPERTENSION[J]. Chinese Circulation Journal, 1993, 0(7) |
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| Authors: | Ruan YingMao Zhu Xiao-Dong Cheng Xian-Sheng et al. |
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| Affiliation: | Ruan YingMao,Zhu Xiao-Dong,Cheng Xian-Sheng,et al. Cardiovascular Institute and Fu Wai Hospital,CAMS,Beijing |
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| Abstract: | A correlative study of the operative effects with the pathologic (by light and electron microscopy) and hemodynamic changes in 16 cases of congenital heart disease with pulmonary hypertension was reported. The dead group consisted of 7 cases while the survival group of 9. Major hypertensive pathologic changes were found in the small pulmonary arteries and arterioles and not in the blood-air barrier of the alveoli. The main differences between the two groups were as follows: pulmonary hypertension, pulmonary arterial resistance and pulmonary hypertensive pathological changes were more severe in the dead group than in the survival. Pulmonary thrombosis, plexiform lesions, hyperplasia of the arterial smooth muscle cells, increase of elastic and collagenous fibers in the arterial wall and interstitiums of the alveoli were more commonly observed in the dead group. |
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| Keywords: | Congenital heart disease Pulmonary hypertensive ultrastructural lesions |
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