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肾上腺髓质素在人类妊娠中的作用研究进展
引用本文:范艳艳,刘依男(综述),付艳(审校). 肾上腺髓质素在人类妊娠中的作用研究进展[J]. 国外医学:妇产科学分册, 2009, 36(1): 4-7
作者姓名:范艳艳  刘依男(综述)  付艳(审校)
作者单位:吉林大学第一医院妇产科;镇江市第一人民医院妇产科;
摘    要:肾上腺髓质素(adrenomedullin,AM)自1993年发现后受到广泛关注,肾上腺髓质素在全身多个系统中均发挥重要作用,主要作用为扩张血管、调节体内水钠代谢、影响细胞增殖和凋亡、抗肿瘤细胞凋亡、促进肿瘤血管生成等,大量研究表明,肾上腺髓质素及其受体在女性生殖内分泌系统中有表达.并且肾上腺髓质素在正常妊娠的胎盘、子宫、母血和脐血中水平增高,并且发现肾上腺髓质素参与子痫前期、妊娠期糖尿病、胎儿生长受限等病理性妊娠过程,提示肾上腺髓质素在妊娠过程中的作用具有多效性。就肾上腺髓质素及其受体在妊娠中的作用综述。

关 键 词:肾上腺髓质素  肾上腺髓质素受体  妊娠  生理性  病理性

The Roles of Adrenomedullin During Human Pregnancy
FAN Yan-yan,LIU Yi-nan,FU Yan.Gynecology , Obstetrics Department in the First Hospital Jilin University,Changchun ,China,The First Peoples' Hospital in Zhenjiang City,Zhenjiang ,China. The Roles of Adrenomedullin During Human Pregnancy[J]. Foreign Medical Sciences(Obstet Gynecol Fascicle), 2009, 36(1): 4-7
Authors:FAN Yan-yan  LIU Yi-nan  FU Yan.Gynecology    Obstetrics Department in the First Hospital Jilin University  Changchun   China  The First Peoples' Hospital in Zhenjiang City  Zhenjiang   China
Affiliation:Fan Yan-yan;FU Yan;LIU Yi-nan
Abstract:Since its discovery in 1993,Adrenomedullin(AM)has been attracting increasing attention.AM has been shown to be widely distributed in peripheral organs,where it contributes to the dilation of vessels,accom-modating the metabolism of liquid and sodium,and participating in the regulation of cell proliferation,apoptosis and angiogenesis in malignant tumors.AM helps maintain the balance in female reproductive-incretion,and the AM concentration in the placenta,uterus,maternal blood and cord blood increases during...
Keywords:Adrenomedullin  Adrenomedullin receptor  Pregnancy  Physiology  Pathology  
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