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Future target-based drug discovery for tuberculosis?
Authors:Bavesh Davandra Kana  Petros C Karakousis  Tanya Parish  Thomas Dick
Institution:1. DST/NRF Centre of Excellence for Biomedical TB Research, Faculty of Health Sciences, University of the Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa;2. Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA;3. Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA;4. TB Discovery Research, Infectious Disease Research Institute, Seattle, WA 98102, USA;5. Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Republic of Singapore;1. Auckland Cancer Society Research Centre, School of Medical Sciences, and Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand;2. Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand;3. Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA;4. Global Alliance for TB Drug Development, 40 Wall St, New York, NY 10005, USA;1. Clinical Microbiology Division, Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu, 180001, India;2. Discovery Informatics, Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu, 180001, India;3. Medicinal Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu, 180001, India;4. Academy of Scientific & Innovative Research (AcSIR), New Delhi, 110001, India
Abstract:
Keywords:Tuberculosis  Drug targets  Drug development  Target vulnerability  Whole-cell screens
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