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Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection
Authors:David A. Magee  Kevin M. Conlon  Nicolas C. Nalpas  John A. Browne  Chris Pirson  Claire Healy  Kirsten E. McLoughlin  Jing Chen  H. Martin Vordermeier  Eamonn Gormley  David E. MacHugh  Stephen V. Gordon
Affiliation:1. Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland;2. UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;3. Department of Bacteriology, Animal Health and Veterinary Laboratories Agency, New Haw, Addlestone, Surrey, United Kingdom;4. Tuberculosis Diagnostics and Immunology Research Centre, UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;5. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland;1. Genotypic Technology Ltd, Bangalore, Karnataka, India;2. Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA;1. State Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China;2. The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National TSE Lab, Beijing 100193, PR China;3. College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China;1. Centro de Investigación y Asistencia en Tecnología y diseño del Estado de Jalisco, A.C., Biotecnología Biomédica, Av. Normalistas 800, Col. Colinas de la Normal, C.P. 44270 Guadalajara, Jalisco, Mexico;2. Instituto Tecnológico de Tlajomulco, Km 10 to San Miguel Cuyutlán, C.P. 45640 Tlajomulco de Zúñiga, Jalisco, Mexico;1. Animal & Bioscience Research Department, Animal & Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, Co. Meath, Ireland;2. Smurfit Institute of Genetics, Trinity College, Dublin 2, Ireland;3. Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada;4. Animal Genomics Laboratory, UCD School of Agriculture and Food Science, UCD College of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;5. UCD School of Veterinary Medicine, UCD College of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;6. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland;1. Ningxia Key laboratory of Clinical and Pathogenic Microbiology, The General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China;2. Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, Ningxia University, Yinchuan, Ningxia 750021, China;3. Department of Laboratory Medicine, College of Clinical Medicine, Ningxia Medical University, Yinchuan, Ningxia 750004, China;4. Department of Microbiology and Immunology, School of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia 750004, China;5. The Center of Experimental Animals, Ningxia Medical University, Yinchuan, Ningxia 750004, China;6. Institute of Human Stem Cell Research, The General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China
Abstract:
Keywords:Alveolar macrophage  Bovine  Cytokine  Gene expression
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