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Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection
Authors:David A Magee  Kevin M Conlon  Nicolas C Nalpas  John A Browne  Chris Pirson  Claire Healy  Kirsten E McLoughlin  Jing Chen  H Martin Vordermeier  Eamonn Gormley  David E MacHugh  Stephen V Gordon
Institution:1. Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland;2. UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;3. Department of Bacteriology, Animal Health and Veterinary Laboratories Agency, New Haw, Addlestone, Surrey, United Kingdom;4. Tuberculosis Diagnostics and Immunology Research Centre, UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;5. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland;1. Genotypic Technology Ltd, Bangalore, Karnataka, India;2. Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA;1. State Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China;2. The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National TSE Lab, Beijing 100193, PR China;3. College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China;1. Centro de Investigación y Asistencia en Tecnología y diseño del Estado de Jalisco, A.C., Biotecnología Biomédica, Av. Normalistas 800, Col. Colinas de la Normal, C.P. 44270 Guadalajara, Jalisco, Mexico;2. Instituto Tecnológico de Tlajomulco, Km 10 to San Miguel Cuyutlán, C.P. 45640 Tlajomulco de Zúñiga, Jalisco, Mexico;1. Animal & Bioscience Research Department, Animal & Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, Co. Meath, Ireland;2. Smurfit Institute of Genetics, Trinity College, Dublin 2, Ireland;3. Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada;4. Animal Genomics Laboratory, UCD School of Agriculture and Food Science, UCD College of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;5. UCD School of Veterinary Medicine, UCD College of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland;6. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland;1. Ningxia Key laboratory of Clinical and Pathogenic Microbiology, The General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China;2. Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, Ningxia University, Yinchuan, Ningxia 750021, China;3. Department of Laboratory Medicine, College of Clinical Medicine, Ningxia Medical University, Yinchuan, Ningxia 750004, China;4. Department of Microbiology and Immunology, School of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia 750004, China;5. The Center of Experimental Animals, Ningxia Medical University, Yinchuan, Ningxia 750004, China;6. Institute of Human Stem Cell Research, The General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China
Abstract:
Keywords:Alveolar macrophage  Bovine  Cytokine  Gene expression
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