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Polyostotic fibrous dysplasia involving the thoracic spine with myelopathy: case report and review of the literature
Authors:Feng Liang Wu  Zhong Jun Liu  Xiao Guang Liu  Shao Min Yang  Liang Jiang  Feng Wei  Miao Yu
Affiliation:1. Orthopaedic Department of Peking University Third Hospital, No 49. North Garden Rd, HaiDian District, Beijing 100191, China;2. Pathology Department of Peking University Health Science Center, No 38. Xue Yuan Rd, HaiDian District, Beijing, 100191, China;1. Department of Orthopaedics and Sports Medicine, University of South Florida, 13220 USF Laurel Dr, Tampa, FL 33612, USA;2. Phillip Spiegel Orthopaedic Research Laboratory, Foundation for Orthopaedic Research and Education, 13020 N. Telecom Parkway, Tampa, FL 33637, USA;3. Center for Spinal Disorders, Florida Orthopaedic Institute, 13020 N. Telecom Parkway, Tampa, FL 33637, USA;1. ORA Orthopedics, 520 Valley View Drive #100, Moline, IL 61265, USA;2. Orthopaedic and Sports Medicine, Harborview Medical Center, 325 Ninth Ave., Box 359798, Seattle, WA 98104-2499, USA;1. Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College St, Toronto, Ontario, Canada M5S 3G9;2. Division of Neurosurgery, St Michael''s Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8;1. Department of Orthopaedic Surgery, Jaber Al-Ahmad Armed Forces Hospital, PO Box 24923, 13110 Safat, Kuwait;2. Department of Radiology, Jaber Al-Ahmad Armed Forces Hospital, Safat, Kuwait;1. Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan;2. Department of Surgical Nursing, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan;1. Department of Neurosurgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA;2. Department of Anesthesiology, Thomas Jefferson University, 3400 Spruce Street, Philadelphia, PA 19107, USA;3. Department of Neurosurgery, Thomas Jefferson University, 111 S 11th Street, Philadelphia, PA 19107, USA
Abstract:Background contextPolyostotic fibrous dysplasia (PFD) seldom involves the thoracic spine and usually presents with back pain.PurposeTo describe an extremely rare presentation of an uncommon disease.Study design/settingWe present a case report from a university hospital.MethodsWe report a case of symptomatic thoracic PFD associated with myelopathy and pathologic fracture. A thorough search of PubMed/MEDLINE was performed for the terms “polyostotic fibrous dysplasia,” “spine,” and “neurological deficit.”ResultsThe patient was treated by posterior laminectomy, vertebroplasty, and pedicle screw fixation and fusion. Satisfactory results were achieved, and there were no complications.ConclusionsIn the spine, PFD may lead to pathologic fracture and myelopathy even after adolescence. Vertebroplasty with or without decompression and fixation may be the appropriate option for cases with myelopathy.
Keywords:Polyostotic fibrous dysplasia  Spine  Myelopathy  Vertebroplasty  Biphosphate
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