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Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised,open-label study
Authors:Grant A McArthur  Paul B Chapman  Caroline Robert  James Larkin  John B Haanen  Reinhard Dummer  Antoni Ribas  David Hogg  Omid Hamid  Paolo A Ascierto  Claus Garbe  Alessandro Testori  Michele Maio  Paul Lorigan  Celeste Lebbé  Thomas Jouary  Dirk Schadendorf  Stephen J O'Day  Axel Hauschild
Affiliation:1. Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia;2. Memorial Sloan Kettering Cancer Center, New York, NY, USA;3. Institut Gustave Roussy, Paris, France;4. Royal Marsden Hospital, London, UK;5. The Netherlands Cancer Institute, Amsterdam, Netherlands;6. University of Zurich, Zurich, Switzerland;7. Jonsson Comprehensive Cancer Center at University of California, Los Angeles, CA, USA;8. Princess Margaret Hospital and University Health Network, Toronto, ON, Canada;9. The Angeles Clinic and Research Institute, Los Angeles, CA, USA;10. Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy;11. The University of Tübingen, Tübingen, Germany;12. Istituto Europeo di Oncologia, Milan, Italy;13. University Hospital of Siena, Istituto Toscano Tumori, Siena, Italy;14. University of Manchester, Manchester, UK;15. APHP Oncodermatology, Hôpital Saint Louis University, Paris, France;p. Saint André Hospital, Bordeaux, France;q. University Hospital Essen, Essen, Germany;r. Beverly Hills Cancer Center, Beverly Hills, CA, USA;s. University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;t. Gustave-Roussy Cancer Center and University Paris-Sud, Villejuif/Paris Sud, France;u. Nantes University Hospital, Nantes, France;v. Vanderbilt University School of Medicine, Nashville, TN, USA;w. Massachusetts General Hospital, Boston, MA, USA;x. Genentech Inc, San Francisco, CA, USA;y. Roche Molecular Systems Inc, Pleasanton, CA, USA;z. F Hoffmann-La Roche, Basel, Switzerland;11. University of Kiel, Kiel, Germany
Abstract:
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