氯乙烯作业工人接触剂量评估和肝功能损伤情况

目的探讨氯乙烯(VCM)对肝脏的损伤作用。方法VCM接触组218人,按VCM接触情况将工人分为高累积剂量组98人〔>1 000 mg/(人.月)〕和低累积剂量组〔<1 000 mg/(人.月)〕120人,另设不接触VCM工人(74名)为对照组。检测工人肝功能和肝B超。结果接触组肝功能异常者33人,发生率为15.14%,对照组肝功能异常者5人,发生率为6.76%;高累积剂量组的肝功能有异常发生率(18.37%)显著高于对照组(6.76%),二者相比,差异有显著性(χ2=4.91,P<0.05)。结论提示VCM对接触工人肝脏损伤作用值得关注。

Exposure Evaluation and Liver Lesion of the Chloroethylene - Exposed Workers

[Objective]To explore the damaging effect of chloroethylene on liver.[Methods]218 workers in the exposure group were divided into two groups: high-cumulation-dose group(more than 1 000 mg/capita.month) and low-cumulation-dose group(less than 1 000 mg/capita.month).74 workers were selected to form the control group.Liver function and liver B-ultrasonic of the workers were detected.[Results]The rate of liver function deficiency in the exposure group and the control group were 15.14% and 6.76% respectively.The rate of liver function deficiency in the high-cumulation-dose group(18.37%) were significantly higher than that in the low-cumulation-dose group(6.76%),the difference was significant(P<0.05).[Conclusion]The damaging effect of chloroethylene on liver shouldn't be ignored.