医院就诊患者华支睾吸虫感染及临床特征分析

目的了解医院就诊患者华支睾吸虫感染情况及临床特点,为采取相应的防治措施提供依据。方法对2010～2011年17 584例就诊患者进行粪检,并分析华支睾吸虫虫卵阳性者的感染情况及实验室检测结果。结果受检者中华支睾吸虫感染2 043例,感染率11.62%,其中男性感染率为18.74%,女性为2.99%,男性显著高于女性(χ2=1052.15,P<0.01),30～岁组感染率最高,为22.15%;民族分布以壮族感染率最高,为29.98%;职业分布以农民感染率最高,为20.06%;有明显症状者1 735例(84.92%);实验室辅助检查中,74.94%感染者(1531例)有嗜酸性粒细胞升高,83.95%(1 715例)感染者有谷氨酰转移酶升高。华支睾吸虫感染者中62.41%有明确的食鱼生史,29.86%食过半生鱼虾。结论医院就诊者华支睾吸虫感染率较高,感染人群分布有明显差异性,应针对易感人群加强宣教等防治工作;对有食鱼生史且伴有嗜酸性粒细胞和谷氨酰转移酶增高患者,应粪检虫卵,以免漏诊。

Analysis of Clonorchis sinensis infection and clinical features of patients seen in hospital

Objective To investigate the prevalence and clinical characteristics of Clonorchis sinensis infection in patients admitted to this hospital to provide a basis for implementing prevention and control measures.Methods Stool specimens were collected from 17 584 patients from Jan.2010 to Jan.2011 and examined.Infection with C.sinensis was determined and laboratory test results were analyzed.Results Of total patients,2 043 were infected with C.sinensis at a rate of 11.62%.The rate of infection for males was 18.74% and that for females was 2.99%.Males had a markedly higher rate of infection than females(χ2=1052.15,P<0.01).By age,patients 30 to 39 years of age had the highest rate of infection(22.15%).By ethnicity,the Zhuang people had the highest rate of infection(29.98%).By occupation,farmers had the highest rate of infection(20.06%).Of all patients,1 735(84.92%) had obvious symptoms.According to laboratory test results,74.94% of patients infected with C.sinensis had an elevated level of eosinophilic granulocytes,and 83.95% had an elevated level of glutamyl transferase(GGT).In terms of habits,62.41% of patients infected with C.sinensis had eaten raw fish,and 29.86% had eaten half-cooked fish or shrimp.Conclusion Patients seen by this hospital had a high rate of infection with C.sinensis.The infected population was markedly distinct.Measures such as improved education should be provided to susceptible populations to prevent and control C.sinensis infection.Stool should be examined for C.sinensis eggs to determine if a patient is infected.Patients who have eaten raw fish or with elevated levels of eosinophilic granulocytes and glutamyl transferase should be tested.