Abstract: | The course; of nine pigs which died shortly after liver transplantation was compared with that of the other nine which survived in a series of 18 consecutive transplants. The only significant differences were found to be the development of an inexorable metabolic acidosis, and the recognition of focal hepatic necrosis observed histologically in the non-survivors. The suggestion is made that progressive hepatic damage may develop, and may cause death in some animals which is not explained on obvious mechanical grounds. |