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Combined human papillomavirus typing and TP53 mutation analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma
Authors:Tamas Daher MD  Mehmet Kemal Tur DMS  Alexander Brobeil MD  Benjamin Etschmann DVM  Biruta Witte MD  Rita Engenhart‐Cabillic MD  Gabriele Krombach MD  Wolfgang Blau MD  Friedrich Grimminger MD  Werner Seeger MD  Jens Peter Klussmann MD  Andreas Bräuninger PhD  Stefan Gattenlöhner MD
Institution:1. Institute of Pathology, University Hospital Giessen, Justus‐Liebig‐University Giessen, Giessen, Germany;2. Department of General and Thoracic Surgery, University Hospital Giessen, Giessen, Germany;3. Department of Radiation Therapy, University Hospital Giessen, Giessen, Germany;4. Department of Diagnostic and Interventional Radiology, University Hospital Giessen, Justus‐Liebig‐University Giessen, Giessen, Germany;5. Department of Internal Medicine V, University Hospital Giessen, Giessen, Germany;6. Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany;7. Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen, Justus‐Liebig‐University Giessen, Giessen, Germany
Abstract:
Keywords:head and neck cancer metastasis  human papillomavirus (HPV)  lung cancer  next generation sequencing  p53
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