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Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells
Authors:Miyoko Matsushima  Kenzo Takagi  Miyuki Ogawa  Etsuko Hirose  Yui Ota  Fumie Abe  Kenji Baba  Takaaki Hasegawa  Yoshinori Hasegawa  Tsutomu Kawabe
Affiliation:(1) MEXT Innovative Research Center for Preventive Medical Engineering, Nagoya University, Furou-cho, Chikusa-ku, Nagoya 464-8603, Japan;(2) Department of Medical Technology, Nagoya University School of Health Sciences, 1-1-20 Daikou-minami, Higashi-ku, Nagoya 461-8673, Japan;(3) Department of Respiratory Medicine, Aichi Medical University School of Medicine, 21 Karimata, Yazako, Nagakute-cho, Aichi 480-1195, Japan;(4) Department of Hospital Pharmacy and Pharmacokinetics, Aichi Medical University School of Medicine, 21 Karimata, Yazako, Nagakute-cho, Aichi 480-1195, Japan;(5) Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
Abstract:

Objective and design  

We investigated the involvement of heme oxygenase (HO)-1 in the anti-allergic action of quercetin against degranulation of rat basophilic leukemia (RBL-2H3) cells, rat peritoneal mast cells, and mouse bone marrow-derived mast cells.
Keywords:
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