Detection of serum MMP-7 and MMP-9 in cholangiocarcinoma patients: evaluation of diagnostic accuracy |
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| Authors: | Kawin Leelawat Sompong Sakchinabut Siriluck Narong Jerasak Wannaprasert |
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| Affiliation: | (1) Department of Surgery, Rajavithi Hospital, Bangkok, 10400, Thailand;(2) Department of Surgery, College of Medicine, Rangsit University, Bangkok, 10400, Thailand |
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| Abstract: | Background Cholangiocarcinoma is an aggressive tumor with a tendency for local invasion and distant metastases. Timely diagnosis is very important because surgical resection (R0) remains the only hope for a cure. However, at present, there is no available tumor marker that can differentiate cholangiocarcinoma from benign bile duct disease. Previous studies have demonstrated that matrix metalloproteinase (MMP)-7 and MMP-9 are frequently expressed in cholangiocarcinoma specimens. |
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