异位嗜铬细胞瘤

目的了解异位嗜铬细胞瘤患者的临床特点,探讨诊断和治疗方法。方法回顾性分析12例异位嗜铬细胞瘤患者的临床表现、定位和定性检查以及治疗效果的资料。结果11例患者表现为持续性高血压,伴阵发性加重。11例测定了血儿茶酚胺,2例同时测定了24h尿儿茶酚胺。6例进行了腔静脉分段取血。8例患者手术治愈,4例患者药物控制良好。结论异位嗜铬细胞瘤以持续性高血压伴阵发性加重表现为主。血儿茶酚胺检查有助于病例诊断。无禁忌症患者应手术治疗。

Ectopic Pheochromocytoma

Objective To investigate the clinic manifestations, diagnosis and treatment of ectopic pheochromocytoma. Methods Twelve cases of ectopic pheochromocytoma were retrospectively analysed.Results Eleven patients had sustained hypertension and paroxysmal elevation of blood pressure. The plasma concentrations of catecholamines and their metabolites were measured. 24 h urinary concentrations of catecholamines and their metabolites were measured in 2 cases. Vena cava samplings were performed in 6 patients. Eight patients were cured after surgical removal of pheochromocytoma while 4 patients received drug therapy and blood pressures were controlled effectively. Conclusion Most patients of ectopic pheochromocytoma are manifested with sustained hypertension and paroxysmal elevation of blood pressure. Vena cava sampling is helpful in difficult differential diagnosis. Surgical removal of pheochromocytoma is the best treatment for patients without contraindications.