梅花针叩刺治疗脾肾两虚夹瘀型糖尿病周围神经病变的临床观察

目的:探讨梅花针叩刺治疗脾肾两虚夹瘀型糖尿病周围神经病变(DPN)的临床效果。方法:选取2015年2月至2018年1月广州市番禺区中医院收治的脾肾两虚夹瘀型DPN患者110例作为研究对象,随机分为对照组(n=50)与观察组(n=60)。对照组给予硫辛酸+甲钴胺治疗,观察组在对照组治疗的基础上给予梅花针叩刺治疗,2组均治疗观察28 d,记录并观察2组的疗效和预后。结果:观察组的总有效率为98.3%,显著高于对照组的88.0%(P<0.05)。治疗后2组的神经电图潜伏期低于治疗前,且波幅高于治疗前,2组比较差异有统计学意义(P<0.05)。2组治疗后正中神经和腓总神经的MNCV、SNCV高于治疗前,且观察组高于对照组,差异均有统计学意义(P<0.05)。治疗后6个月随访,观察组的复发率为1.7%,显著低于对照组的14.0%,差异有统计学意义(P<0.05)。结论:梅花针叩刺治疗脾肾两虚夹瘀型DPN能改善神经功能指标,提高治疗效果,降低远期复发率。

Clinical Observation on Treatment of Diabetic Peripheral Neuropathy with Spleen-kidney Deficiency Complicated by Stasis Type by the Plum-blossom Needle

Objective:To investigate effects of diabetic peripheral neuropathy(DPN)with spleen-kidney deficiency by stasis type by the plum-blossom needle.Methods:From February 2015 to January 2018,a total of 110 cases of DPN with spleen-kidney deficiency by stasis type in Panyu Hospital of Chinese Medicinewere selected as the research objects and were divided into an observation group(60 cases)and a control group(50 cases)accorded to different treatment methods.The control group were treated with lipoic acid+mecobalamin,and the observation group were given the plum-blossom needle based on the control group.The 2 groups were treated 28 days and the prognosis of the 2 groups were recorded and observed.Results:The total effective rates of the observation group were 98.3%,which were significantly higher than that of the control group(88.0%)(P<0.05).The latency of the electroencephalogram was lower than that before treatment,and the amplitude were higher than that before treatment.The differences was statistically significant(P<0.05).There were also significant difference in the difference compared between the observation group and the control group after treatment(P<0.05).The MNCV and SNCV of the median nerve and common peroneal nerve in the 2 groups after treatment were higher than those before treatment,and the observation group were higher than the control group and differences were statistically significant(P<0.05).The followed-up recurrence rates in the 6 month of the observation group were 1.7%,which were significantly lower than the control group of 14.0%(P<0.05).Conclusion:Plum-blossom needle treatment of DPN with spleen-kidney deficiency by stasis type can improve neurological function,improve treatment effects and reduce long-term recurrence rate.