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Probable Creutzfeldt-Jakob disease after a cadaveric dural graft
Authors:Prof. Dr med. C. J. G. Lang  P. Schüler  A. Engelhardt  A. Spring  P. Brown
Affiliation:(1) Neurologische Klinik der Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany;(2) Neurochirurgische Klinik des Leopoldina-Krankenhauses der Stadt Schweinfurt, Schweinfurt, Germany;(3) Laboratory of Central Nervous System Studies, National Institutes of Health, Bethesda, Maryland, USA
Abstract:A 26-year old female who had received a cervical cadaveric dural graft 7 years earlier developed psychotic behavior and generalized myoclonic jerks. Following rapid deterioration and appearance of high-charge sharp periodic waves on electroencephalography she died within two months. We believe that this patient is the first German who acquired Creutzfeldt-Jakob disease by dural implant.
Keywords:Creutzfeldt-jakob disease  Dural graft  Transmission
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