A population-based study of chronic pancreatitis in Finland: Effects on quality of life |
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| Affiliation: | 1. Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland;2. Dept of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland;1. College of Medicine, University of Florida, Gainesville, FL, USA;2. Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA;3. Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, USA;4. Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA;5. Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA;6. Department of Diagnostic Radiology, Moffitt Cancer Center, Tampa, FL, USA;1. Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India;2. Section of GI Radiology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India;3. Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India;1. Department of Medicine, Division of Digestive and Liver Diseases, Columbia University Irving Medical Center, NY, USA;2. Pancreas Center, Division of Surgery, Columbia University Irving Medical Center, NY, USA;3. Larner College of Medicine at the University of Vermont, Burlington, VT, USA;4. Division of Gastroenterology and Hepatology, New York University, New York, NY;1. Saglik Bilimleri University, Van Education and Research Hospital, Department of Internal Medicine, Clinic of Gastroenterology and Hepatology, Van, Turkey;2. Saglik Bilimleri University, Van Education and Research Hospital, Department of Internal Medicine, Van, Turkey |
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| Abstract: | Background/ObjectivesIn Finland the incidence of chronic pancreatitis (CP) is high compared to that in most European countries. Recent epidemiological data is lacking. Our aim was to investigate the current epidemiologic and behavioural data on CP patients in Finland.MethodsCP patients according to M-ANNHEIM criteria in Tampere University Hospital (TAUH) during 2014–2015 were included. Aetiology, time from diagnosis, pancreatic function, treatment, complications, smoking, alcohol consumption (AUDIT) and quality of life (QoL) (QLQ C30, PAN26) were gathered.Results235 CP patients (57 (26–88) years, 65% men) were included. Time since diagnosis was 5.5 (1–41) years. Aetiology was alcohol in 67%, and smoking contributed in 54%. Of these patients 78% continued smoking and 58% continued to consume alcohol even after CP diagnosis. CP related complications were common. Pseudocysts were more common in alcohol related CP than in non-alcohol related CP (60% vs. 38%, p < 0.05). Reported QoL and pain were worse in the CP patients than in controls. Alcohol consumption differed from that of the Finnish population; the CP patients were either total abstainers or heavy alcohol consumers.ConclusionsCP constitutes a great burden on the health care system and on the patients. The patients frequently develop complications and symptoms and their QoL is inferior to that of controls. The most important measure to halt the progression of CP would be to prevent acute phases and for patients to stop smoking, which does not happen in many CP patients. It would be beneficial to increase awareness among CP patients and medical professionals. |
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| Keywords: | Aetiology Alcohol Chronic pancreatitis Smoking Quality of life |
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