Two distinct STLV-1 subtypes infecting Mandrillus sphinx follow the geographic distribution of their hosts |
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| Authors: | Makuwa M Souquière S Clifford S L Telfer P T Sallé B Bourry O Onanga R Mouinga-Ondeme A Wickings E J Abernethy K A Rouquet P Simon F Roques P |
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| Affiliation: | Laboratoire de Virologie, UGENET, CDP, SEGC-Lopé, Centre International de Recherches Médicales, Franceville, Gabon. mmakuwa@yahoo.com |
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| Abstract: | The mandrill (Mandrillus sphinx) has been shown to be infected with an STLV-1 closely related to HTLV-1. Two distinct STLV-1 subtypes (D and F) infect wild mandrills with high overall prevalence (27.0%) but are different with respect to their phylogenetic relationship and parallel to the mandrills' geographic range. The clustering of these new STLV-1mnd sequences with HTLV-1 subtype D and F suggests first, past simian-to-human transmissions in Central Africa and second, that species barriers are easier to cross over than geographic barriers. |
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