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Tumor-and osteoclast-derived NRP2 in prostate cancer bone metastases
Authors:Navatha Shree Polavaram  Samikshan Dutta  Ridwan Islam  Arup K.Bag  Sohini Roy  David Poitz  Jeffrey Karnes  Lorenz C.Hofbauer  Manish Kohli  Brian A.Costello  Raffael Jimenez  Surinder K.Batra  Benjamin A.Teply  Michael H.Muders  Kaustubh Datta
Affiliation:Department of Microbiology and Pathology,University of Nebraska Medical Center,Omaha,NE,USA;Department of Biochemistry and Molecular Biology,University of Nebraska Medical Center,Omaha,NE,USA;Institute for Clinical Chemistry,University Hospital Dresden,Dresden,Germany;Department of Urology,Mayo Clinic,Rochester,MN,USA;Center for Healthy Aging and Bone Lab Dresden,Department of Medicine Ⅲ,Technische Universit?t Dresden,Dresden,Germany;School of Medicine,Division of Oncology,Huntsman Cancer Institute,Salt Lake City,UT,USA;Division of Anatomic Pathology,Department of Pathology and Laboratory Medicine,Mayo Clinic,Rochester,MN,USA;Internal Medicine,Division of Oncology&Hematology,University of Nebraska Medical Center,Omaha,NE,USA;Rudolf-Becker Laboratory for Prostate Cancer Research,Institute of Pathology,University of Bonn Medical Center,Bonn,Germany
Abstract:INTRODUCTIONBone is the most common metastatic site for castration-resistant prostate cancer.1 Nearly 70%–80% of the patients with advanced-stage prostate canc...
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