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Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling
Authors:Tarek Mohamed Abd El-Aziz  Yucheng Xiao  Jake Kline  Harold Gridley  Alyse Heaston  Klaus D Linse  Micaiah J Ward  Darin R Rokyta  James D Stockand  Theodore R Cummins  Luca Fornelli  Ashlee H Rowe
Abstract:
Keywords:voltage-gated sodium channel  Nav1  8  hyperpolarization  pain signaling  scorpion venom  neurotoxin  bioactive proteins  drug discovery  Onychomys torridus  Centruroides sculpturatus
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