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Importance of Considering Malnutrition and Sarcopenia in Order to Improve the QOL of Elderly Hemodialysis Patients in Japan in the Era of 100-Year Life
Authors:Masaaki Inaba  Senji Okuno  Yoshiteru Ohno
Institution:1.Department of Nephrology, Osaka City University Medical School, 1-4-3 Asahi-machi, Abeno-ku, Osaka 543-8585, Japan;2.Kidney Center, Ohno Memorial Hospital, 1-26-10, Minami-Horie, Nishi-ku, Osaka 550-0015, Japan;3.Kidney Center, Shirasagi Hospital, 7-11-23, Higashisumiyoshi-ku, Osaka 546-0002, Japan;
Abstract:In the current aging society of Japan, malnutrition and resultant sarcopenia have been widely identified as important symptomatic indicators of ill health and can cause impairments of longevity and quality of life in older individuals. Elderly individuals are recommended to have sufficient calorie and protein intake so as to enjoy a satisfactory quality of life, including maintaining activities of daily living in order to avoid emaciation and sarcopenia. The prevalence of emaciation and sarcopenia in elderly hemodialysis (HD) patients in Japan is higher than in non-HD elderly subjects due to the presence of malnutrition and sarcopenia associated with chronic kidney disease (CKD). Furthermore, comorbidities, such as diabetes and osteoporosis, induce malnutrition and sarcopenia in HD patients. This review presents findings regarding the mechanisms of the development of these early symptomatic conditions and their significance for impaired QOL and increased mortality in elderly HD patients.
Keywords:clinical malnutrition  older individuals  hemodialysis  sarcopenia  chronic kidney disease  quality of life  mortality
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