| 海拔4300m世居和移居青年血清细胞间粘附分子—1的表达 |
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| 引用本文： | 崔建华 张西洲. 海拔4300m世居和移居青年血清细胞间粘附分子—1的表达[J]. 高原医学杂志, 2000, 10(3): 26-28 |
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| 作者姓名： | 崔建华 张西洲 |
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| 作者单位： | 解放军第18医院!844900(崔建华，张西洲，朱国斌，何富文)，军事医学科学院卫生学环境医学研究所!300050(谢印芝)，西藏阿里军分区卫生所!850000(高江峰) |
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| 摘 要： | 目的：观察高原民居和移居青年血管内皮细胞间粘附分子－１（ＩＣＡＭ－１）的表达；方法：在海拔４３００ｍ对２０名藏族青年和２０名汉族青年运用酶联免疫分析法（ＥＬＩＳＡ）进行血清ＩＣＡＭ－１含量检测；结果：高原移居汉族青年较世居藏族青年血清ＩＣＡＭ的表达增强（Ｐ〈０．０５）；结论：低氧引志内皮细胞粘附分子的表达增强，促进循环白细胞与内皮细胞粘附。高原世居藏族对氧的利用更经济有效，具有最佳的生理适应模式，
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| 关 键 词： | 高原 世居 移居 ICAM－1 血清 |
SERUM INTERCELLULAP ADCHESION MOLECULE EXPRESSION OF THE NATIVE AND MIGRATED YOUTHS AT 4 300m ALTITUDE |
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| Cui Jianhua,et al The Hospital of PLA. SERUM INTERCELLULAP ADCHESION MOLECULE EXPRESSION OF THE NATIVE AND MIGRATED YOUTHS AT 4 300m ALTITUDE[J]. Journal of High Altitude Medicine, 2000, 10(3): 26-28 |
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| Authors: | Cui Jianhua et al The Hospital of PLA |
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| Affiliation: | Cui Jianhua,et al The 18 Hospital of PLA |
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| Abstract: | Objective:To observe intercellular aschesion molecule (ICAM-1)expression of the native and migrated youths at high altitude.Methods:Serum level of ICAM-1 in 40 youths (20 native tibetan,20 migrated Han nationality)were measured by ELISA at 4 300m altitude. Results:Expression of ICAM-1 in native group was obviously enhanced (P<0.05) than that of migrated group.Conclusion:There is a strengthening effect of high altitude hypoxia on ICAM-1 expression so that intercellula molecule adchesion is promoted with increasing WBC.This result shows that the hypoxic adaptation of native tibetan is better on use of most oxygen. |
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| Keywords: | High altitude Serum Adchesion molecule Expression Youths Tibetan Han nationality Adaptation Native Migration |
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