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Relationship between Different Pronuclear Patterns and Potential of Embryo Development and Pregnancy
引用本文:Zhong-meiLI Yu-baoWANG Dun-yuGU Xiao-yunWU De-qiJIANG ZhenLU Zuan-chongFENG. Relationship between Different Pronuclear Patterns and Potential of Embryo Development and Pregnancy[J]. 生殖与避孕(英文版), 2003, 14(2): 99-104
作者姓名:Zhong-meiLI Yu-baoWANG Dun-yuGU Xiao-yunWU De-qiJIANG ZhenLU Zuan-chongFENG
作者单位:InfertilityandIVFCenterofShanghaiInstituteofPlannedParenthoodResearch,Shanghai,200032,China
摘    要:Objective To explore the relationship between the patterns of pronucleus and embryo development and pregnancy potential in the pronuclear stageand. Methods According to the number and distribution of nucleolar precursor bodies, the embryos at pronuclear stage were classified into 6 pronuclear patterns from 0 to g, 16~18 h after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). For each pattern, the subsequent embryonic morphology and the pregnancy rate were analyzed. Results Embryos of Pattern 0 developed to significantly more embryos with good quality and higher pregnancy potential than the embryos developing from other patterns (83. 14% and 76. 11% respectively, P<0. 05). The pregnancy rate was decreased as less embryosgroups of only Patternof O,attern O were transferred . The pregnancy rate of the with Pattern O, and withoutPattern O were 48. 08%, 32. 14% and 21.28% respectively (P<0. 05). Conclusions The pronuclear patterns are of the predictive value of embryo development and pregnancy potential, which can be used as a new tool for the selection of embryos in IVF and ICSI.

关 键 词:胚胎选择 IVF 胚胎发育 怀孕 ICSI 核仁前体 原核模式 体外受精

Relationship between Different Pronuclear Patterns and Potential of Embryo Development and Pregnancy
Zhong-mei LI,Yu-bao WANG,Dun-yu GU,Xiao-yun WU,De-qi JIANG,Zhen LU,Zuan-chong FENG. Relationship between Different Pronuclear Patterns and Potential of Embryo Development and Pregnancy[J]. Journal of Reproduction and Contraception, 2003, 14(2): 99-104
Authors:Zhong-mei LI  Yu-bao WANG  Dun-yu GU  Xiao-yun WU  De-qi JIANG  Zhen LU  Zuan-chong FENG
Abstract:Objective To explore the relationship between the patterns of pronucleus and embryo development and pregnancy potential in the pronuclear stageMethods According to the number and distribution of nucleolar precursor bodies, the embryos at pronuclear stage were classified into 6 pronuclear patterns from 0 to 5, 16 - 18 h after in vitro fertilization (IV F) or intracytoplasmic sperm injection (ICSI). For each, pattern, the subsequent embryonic morphology and the pregnancy rate were analyzed.Results Embryos of Pattern 0 developed to significantly more embryos with good quality and higher pregnancy potential than the embryos developing from other patterns (83. 14% and 76. 11% respectively, P<0. 05). The pregnancy rate was decreased as less embryos of Pattern 0 were transferred . The pregnancy rate of the groups of only Pattern 0, with Pattern 0, and without Pattern 0 were 48. 08% , 32. 14% and 21. 28% respectively (P<0. 05).Conclusions The pronuclear patterns are of the predictive value of embryo development and pregnancy potential, which can be used as a new tool for the selection of embryos in IVF and ICSI.
Keywords:pronuclear pattern  embryo selection  IVF  embryo development
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