煤工尘肺复治肺结核两种治疗方案疗效分析

目的　探讨煤工尘肺结核复治病例较佳的治疗方案。方法 对出院的煤工尘肺结核复治病例中应用3SHRZ/3HRZE/12HRE194例和3SHRZ/9HRE72例抗痨治疗疗效作回顾性分析。结果 痰菌阴转率:治疗6个月和疗程结束后,两种方案痰菌阴转率有显著性差异(P<0.05);胸片好转率也有显著性差别(P<0.05)。结论 煤工尘肺结核复治病例的治疗,采用3SHRZ/3HRZE/12HRE方案,即强化阶段6个月、疗程18个月疗效较满意,不宜采用12个月疗程化疗。

An analysis on the therapeutic effect of 3SHRZ/3HRZE/12HRE and 3SHRZ/9HRE on coal worker's pneumoconiosis-tuberculosis

Objective To probe into the better retreatment scheme for the coal worker's pneumoconiosis-tuberculosis treatment. Methods Analyse the therapeutic effect and the anti-tuberculosis treatment in the case in which 194 3SHRZ/3HRZE/12HRE and 73 3SHRZ/9HRE were applied on these patients who had been discharged from hospital. Results After 6 months treatment,both of these 2 treatment schemes were obviously different in the sputum tubercle bacillus negative convertion-rate on all kinds of the coal worker's pneumoconisis-tuberculosis(P<0.05); and so were they on the redution-rate of chest X-ray after the course of treatment (P<0.05). Conclusion The 6-month strengthened period-the scheme of the 3SHRZ/3HRZE/12HRE applied on the reteatment of the coal worker's pneumoconiosis-tuberculosis case,and the course of treatment was as long as 18 months. The therapeutic effect was quite satisfactory,so it is not appropriate to apply the 12-month scheme.