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| 神经纤维蛋白在神经生长锥的表达和定位 | |
| 引用本文： | 翟秀岩,马文锋,刘庆华,海佐保子. 神经纤维蛋白在神经生长锥的表达和定位[J]. 解剖科学进展, 2002, 8(2): 115-117 |
| 作者姓名： | 翟秀岩 马文锋 刘庆华 海佐保子 |
| 作者单位： | 1. 中国医科大学发育生物学研究室 2. 中国医科大学附属第一医院外科,辽宁,沈阳,110001 3. 齐齐哈尔大学生物系 4. 日本山梨医科大学解剖第二讲座,山梨,409-3898 |
| 摘 要： | 目的 探索神经纤维蛋白 (neurofilamentprotein ,NFP)在神经生长锥的表达及其机能意义。方法 采用免疫双荧光染色法 ,以荧光显微镜观察NFP在初代培养脊神经节细胞生长锥的表达及其定位特征。结果 NFP密集分布在细胞质中、神经突起内 ,延伸至生长锥体部的C区内 ;结论 NFP是构成生长锥的细胞骨架成分之一 ;参与神经突起及生长锥的物质运输活动 |
| 关 键 词： | 生长锥 NFP 脊神经节细胞 初代培养 |
| 文章编号： | 1006-2947(2002)02-0115-03 |
| 修稿时间： | 2002-03-15 |
Expression and Location of Neurofilament Protein in the Nerve Growth Cones |
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| ZHAI Xiu-yan ,MA Wen-feng ,LIU Qing-hua ,ASTMI Saoko. Expression and Location of Neurofilament Protein in the Nerve Growth Cones[J]. Progress of Anatomical Sciences, 2002, 8(2): 115-117 | |
| Authors: | ZHAI Xiu-yan MA Wen-feng LIU Qing-hua ASTMI Saoko |
| Affiliation: | ZHAI Xiu-yan 1,MA Wen-feng 2,LIU Qing-hua 3,ASTMI Saoko 4 |
| Abstract: | Objective To investigate the expression and functional significance of neurofilament protein (NFP) in the nerve growth cones. Method We observed the expression and location of NFP in the nerve growth cones of primarily cultured chicken embryo spinal ganglion cells by using double immunofluorescent method with fluorescent microscope. Result NFP is intensely distributed in the cytoplasma, nerve process, and elongated to C domain of nerve growth cone body. Conclusion NFP is one kind of cytoskeleton, and involved in the transportation in the nerve growth cones and nerve process. |
| Keywords: | nerve growth cone neurofilament protein spinal ganglion cell primarily culture |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |