| 应用13C核磁共振INEPT方法测定5α-氯-16-次甲基-3β,6β,17α-三羟基-孕甾-20-酮-3β,17α二醋酸酯的结构 |
| |
| 引用本文： | 孟怡,顾娟. 应用13C核磁共振INEPT方法测定5α-氯-16-次甲基-3β,6β,17α-三羟基-孕甾-20-酮-3β,17α二醋酸酯的结构[J]. 药学学报, 1988, 23(4): 288-292 |
| |
| 作者姓名： | 孟怡 顾娟 |
| |
| 作者单位： | 中国药科大学,南京 |
| |
| 摘 要： | 应用质子去偶及质子偶合INEPT方法测定药物合成中间体(Ⅱ)的结构。与宽带质子去偶及门控去偶方法比较,INEPT方法具有较高的灵敏度和选择性,节省实验时间。
|
| 关 键 词： | INEPT 多脉冲序列方法 13CNMR 甾体化合物 |
| 收稿时间： | 1987-01-14 |
Application of 13CNMR INEPT technic to structure determination of 5 alpha-chlorine-16-methylene-3 beta, 6 beta, 17 alpha-trihydroxypregnan-20-one-3, 17-diacetate |
| |
| Y Meng and J Gu. Application of 13CNMR INEPT technic to structure determination of 5 alpha-chlorine-16-methylene-3 beta, 6 beta, 17 alpha-trihydroxypregnan-20-one-3, 17-diacetate[J]. Acta pharmaceutica Sinica, 1988, 23(4): 288-292 |
| |
| Authors: | Y Meng and J Gu |
| |
| Abstract: | 5α-Chlorine-16-methylene-3β, 6β, 17α-trihydroxypregnan-20-one 3, 17-diacetate has been examined to confirm the key structure using proton deeoupled and coupled INEPT technique. By comparison with the proton broadband decoupling and gated deccupling assignment techniques, the INEPT methods showed higher sensitivity, selectivity and time-efficiency. |
| |
| Keywords: | Multipulse sequence method 13CNMR Steroid Insensitive nuclei enhancement by polarization transfer |
|
| 点击此处可从《药学学报》浏览原始摘要信息 |
|
点击此处可从《药学学报》下载全文 |
|
